| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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138 genes differentially expressed following the BRD-A77824596_FLUOCINOLONE ACETONIDE_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AARS | alanyl-tRNA synthetase |
| ADAM10 | ADAM metallopeptidase domain 10 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CALD1 | caldesmon 1 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CD24 | CD24 molecule |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 |
| CXADR | coxsackie virus and adenovirus receptor |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| DBN1 | drebrin 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| EHBP1 | EH domain binding protein 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FBXL12 | F-box and leucine-rich repeat protein 12 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLNA | filamin A, alpha |
| FN1 | fibronectin 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| JADE2 | jade family PHD finger 2 |
| JAG1 | jagged 1 |
| KLF9 | Kruppel-like factor 9 |
| KRT13 | keratin 13, type I |
| KRT15 | keratin 15, type I |
| KRT7 | keratin 7, type II |
| LAMA4 | laminin, alpha 4 |
| LAMB1 | laminin, beta 1 |
| LDLR | low density lipoprotein receptor |
| MAOA | monoamine oxidase A |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MEST | mesoderm specific transcript |
| MFN2 | mitofusin 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MME | membrane metallo-endopeptidase |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1X | metallothionein 1X |
| MUC4 | mucin 4, cell surface associated |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| OSBPL10 | oxysterol binding protein-like 10 |
| PDLIM5 | PDZ and LIM domain 5 |
| POU2AF1 | POU class 2 associating factor 1 |
| PTPRK | protein tyrosine phosphatase, receptor type, K |
| RGS5 | regulator of G-protein signaling 5 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RTN2 | reticulon 2 |
| SFRP1 | secreted frizzled-related protein 1 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SOX11 | SRY (sex determining region Y)-box 11 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TSC22D3 | TSC22 domain family, member 3 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| ANXA1 | annexin A1 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit |
| ARG1 | arginase 1 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| CCNE2 | cyclin E2 |
| CCNH | cyclin H |
| CETN3 | centrin, EF-hand protein, 3 |
| CLDN3 | claudin 3 |
| CLGN | calmegin |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DACH1 | dachshund family transcription factor 1 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| EFHD1 | EF-hand domain family, member D1 |
| ESR1 | estrogen receptor 1 |
| FAM129A | family with sequence similarity 129, member A |
| FBLN5 | fibulin 5 |
| G0S2 | G0/G1 switch 2 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GCA | grancalcin, EF-hand calcium binding protein |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HAL | histidine ammonia-lyase |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H4C | histone cluster 1, H4c |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| IER3 | immediate early response 3 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| LAGE3 | L antigen family, member 3 |
| LAMC2 | laminin, gamma 2 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LYRM1 | LYR motif containing 1 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MBP | myelin basic protein |
| MCUR1 | mitochondrial calcium uniporter regulator 1 |
| MFAP4 | microfibrillar-associated protein 4 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| NGRN | neugrin, neurite outgrowth associated |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PHYH | phytanoyl-CoA 2-hydroxylase |
| PIP | prolactin-induced protein |
| PROM1 | prominin 1 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 |
| PTN | pleiotrophin |
| RAB4A | RAB4A, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RGS2 | regulator of G-protein signaling 2 |
| RPL37A | ribosomal protein L37a |
| RPS11 | ribosomal protein S11 |
| RRAGD | Ras-related GTP binding D |
| S100A12 | S100 calcium binding protein A12 |
| SFN | stratifin |
| SKP1 | S-phase kinase-associated protein 1 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPARCL1 | SPARC-like 1 (hevin) |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TEX30 | testis expressed 30 |
| TSPAN5 | tetraspanin 5 |
| TSPAN7 | tetraspanin 7 |
| TSPAN8 | tetraspanin 8 |
| TUFT1 | tuftelin 1 |
