| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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123 genes differentially expressed following the BRD-A79768653_sirolimus_HS578T_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADA | adenosine deaminase |
| ALCAM | activated leukocyte cell adhesion molecule |
| AMOTL2 | angiomotin like 2 |
| AREG | amphiregulin |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ASS1 | argininosuccinate synthase 1 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BEX4 | brain expressed, X-linked 4 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CALCRL | calcitonin receptor-like |
| CCR7 | chemokine (C-C motif) receptor 7 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| COL11A1 | collagen, type XI, alpha 1 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTGF | connective tissue growth factor |
| CTSH | cathepsin H |
| EDN1 | endothelin 1 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFNB2 | ephrin-B2 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FN1 | fibronectin 1 |
| FOXO1 | forkhead box O1 |
| GPC4 | glypican 4 |
| HLA-E | major histocompatibility complex, class I, E |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| INSR | insulin receptor |
| IRS2 | insulin receptor substrate 2 |
| ITGAV | integrin, alpha V |
| JAG1 | jagged 1 |
| LBH | limb bud and heart development |
| LCN2 | lipocalin 2 |
| MIR22HG | MIR22 host gene |
| MME | membrane metallo-endopeptidase |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NNMT | nicotinamide N-methyltransferase |
| NPY | neuropeptide Y |
| NTS | neurotensin |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PLA1A | phospholipase A1 member A |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PROM1 | prominin 1 |
| RAB13 | RAB13, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| S100A8 | S100 calcium binding protein A8 |
| SELL | selectin L |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SULF1 | sulfatase 1 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| THBS1 | thrombospondin 1 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| VCAN | versican |
| VNN1 | vanin 1 |
| Symbol | Name |
|---|---|
| AK4 | adenylate kinase 4 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| AURKB | aurora kinase B |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| CAST | calpastatin |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CENPU | centromere protein U |
| CFH | complement factor H |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FABP7 | fatty acid binding protein 7, brain |
| FAM162A | family with sequence similarity 162, member A |
| FEN1 | flap structure-specific endonuclease 1 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GPI | glucose-6-phosphate isomerase |
| HK2 | hexokinase 2 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 |
| KRT19 | keratin 19, type I |
| LAMA3 | laminin, alpha 3 |
| LAP3 | leucine aminopeptidase 3 |
| LIG1 | ligase I, DNA, ATP-dependent |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MELK | maternal embryonic leucine zipper kinase |
| METTL7A | methyltransferase like 7A |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NET1 | neuroepithelial cell transforming 1 |
| PCNA | proliferating cell nuclear antigen |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 |
| PFKP | phosphofructokinase, platelet |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PNP | purine nucleoside phosphorylase |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| S100A10 | S100 calcium binding protein A10 |
| S100A2 | S100 calcium binding protein A2 |
| SDC1 | syndecan 1 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SPP1 | secreted phosphoprotein 1 |
| SRGN | serglycin |
| TMEM97 | transmembrane protein 97 |
| VEGFA | vascular endothelial growth factor A |
