| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
110 genes differentially expressed following the BRD-A79768653_sirolimus_LNCAP_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADIRF | adipogenesis regulatory factor |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| AIM1 | absent in melanoma 1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BCL2L1 | BCL2-like 1 |
| CD24 | CD24 molecule |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD9 | CD9 molecule |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| HBB | hemoglobin, beta |
| IDS | iduronate 2-sulfatase |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IRS2 | insulin receptor substrate 2 |
| KIAA1033 | KIAA1033 |
| KLK2 | kallikrein-related peptidase 2 |
| LAMA5 | laminin, alpha 5 |
| LAMC2 | laminin, gamma 2 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MAGED1 | melanoma antigen family D1 |
| MAGED2 | melanoma antigen family D2 |
| MAMLD1 | mastermind-like domain containing 1 |
| MDK | midkine (neurite growth-promoting factor 2) |
| MSMB | microseminoprotein, beta- |
| MYO5C | myosin VC |
| NKX3-1 | NK3 homeobox 1 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PEG3 | paternally expressed 3 |
| PENK | proenkephalin |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
| PTGES | prostaglandin E synthase |
| PTN | pleiotrophin |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RGS2 | regulator of G-protein signaling 2 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SMAD3 | SMAD family member 3 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| SPP1 | secreted phosphoprotein 1 |
| SRGN | serglycin |
| TNS1 | tensin 1 |
| TSPAN6 | tetraspanin 6 |
| TSPYL5 | TSPY-like 5 |
| UPK1B | uroplakin 1B |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| CCDC86 | coiled-coil domain containing 86 |
| CCNA2 | cyclin A2 |
| CCND2 | cyclin D2 |
| CCNE2 | cyclin E2 |
| CDC25B | cell division cycle 25B |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLIC4 | chloride intracellular channel 4 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| E2F2 | E2F transcription factor 2 |
| EBP | emopamil binding protein (sterol isomerase) |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAS | Fas cell surface death receptor |
| FCGBP | Fc fragment of IgG binding protein |
| FEN1 | flap structure-specific endonuclease 1 |
| FOXM1 | forkhead box M1 |
| GARS | glycyl-tRNA synthetase |
| IGHM | immunoglobulin heavy constant mu |
| JUN | jun proto-oncogene |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MELK | maternal embryonic leucine zipper kinase |
| MREG | melanoregulin |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NCAM1 | neural cell adhesion molecule 1 |
| NUP85 | nucleoporin 85kDa |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PHGDH | phosphoglycerate dehydrogenase |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RRM2 | ribonucleotide reductase M2 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TPX2 | TPX2, microtubule-associated |
| TRIB3 | tribbles pseudokinase 3 |
| TRIP13 | thyroid hormone receptor interactor 13 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| WARS | tryptophanyl-tRNA synthetase |
| YARS | tyrosyl-tRNA synthetase |
