BRD-A86109770_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-A86109770_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CA2 carbonic anhydrase II
CLIC4 chloride intracellular channel 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
RPS4Y1 ribosomal protein S4, Y-linked 1
SHB Src homology 2 domain containing adaptor protein B
SQSTM1 sequestosome 1
THBD thrombomodulin
TMEM176B transmembrane protein 176B
TXNRD1 thioredoxin reductase 1
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
GNG11 guanine nucleotide binding protein (G protein), gamma 11
IFITM1 interferon induced transmembrane protein 1
IRS2 insulin receptor substrate 2
MYOF myoferlin
NTS neurotensin
SPINK1 serine peptidase inhibitor, Kazal type 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase