BRD-A87137733_GSK-690693_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-A87137733_GSK-690693_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCNG2 cyclin G2
CD36 CD36 molecule (thrombospondin receptor)
CDK19 cyclin-dependent kinase 19
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
COL15A1 collagen, type XV, alpha 1
DLK1 delta-like 1 homolog (Drosophila)
DSP desmoplakin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FLRT2 fibronectin leucine rich transmembrane protein 2
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GALC galactosylceramidase
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IGL immunoglobulin lambda locus
IRS2 insulin receptor substrate 2
OPN3 opsin 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
RAP1GAP RAP1 GTPase activating protein
SLC38A2 solute carrier family 38, member 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIM29 tripartite motif containing 29
TSC22D3 TSC22 domain family, member 3
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AXL AXL receptor tyrosine kinase
CCND1 cyclin D1
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CORO1C coronin, actin binding protein, 1C
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
EGR3 early growth response 3
F3 coagulation factor III (thromboplastin, tissue factor)
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FOSL1 FOS-like antigen 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBEGF heparin-binding EGF-like growth factor
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER3 immediate early response 3
KLF6 Kruppel-like factor 6
LIF leukemia inhibitory factor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAT2A methionine adenosyltransferase II, alpha
MCL1 myeloid cell leukemia 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NR4A3 nuclear receptor subfamily 4, group A, member 3
OLFM4 olfactomedin 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PSPH phosphoserine phosphatase
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RGS2 regulator of G-protein signaling 2
SLC25A46 solute carrier family 25, member 46
TFF3 trefoil factor 3 (intestinal)
TMEM45A transmembrane protein 45A
TMSB15A thymosin beta 15a
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TSPAN1 tetraspanin 1
UBE2S ubiquitin-conjugating enzyme E2S
UGCG UDP-glucose ceramide glucosyltransferase
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