Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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77 genes differentially expressed following the BRD-A87137733_GSK-690693_HS578T_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ASMTL | acetylserotonin O-methyltransferase-like |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CLDN10 | claudin 10 |
CTSA | cathepsin A |
CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DUSP6 | dual specificity phosphatase 6 |
FAM46A | family with sequence similarity 46, member A |
FOXO4 | forkhead box O4 |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IRS2 | insulin receptor substrate 2 |
KLF2 | Kruppel-like factor 2 |
LAMB2 | laminin, beta 2 (laminin S) |
MAP7 | microtubule-associated protein 7 |
MTSS1 | metastasis suppressor 1 |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
NNMT | nicotinamide N-methyltransferase |
P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
PDZK1IP1 | PDZK1 interacting protein 1 |
QPCT | glutaminyl-peptide cyclotransferase |
RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
RBKS | ribokinase |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
S100A9 | S100 calcium binding protein A9 |
SOX4 | SRY (sex determining region Y)-box 4 |
TACC2 | transforming, acidic coiled-coil containing protein 2 |
TFF1 | trefoil factor 1 |
TFF3 | trefoil factor 3 (intestinal) |
TM4SF1 | transmembrane 4 L six family member 1 |
TSC22D1 | TSC22 domain family, member 1 |
YPEL5 | yippee-like 5 (Drosophila) |
Symbol | Name |
---|---|
AK4 | adenylate kinase 4 |
ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
ANPEP | alanyl (membrane) aminopeptidase |
AP1S2 | adaptor-related protein complex 1, sigma 2 subunit |
CADM1 | cell adhesion molecule 1 |
CDC20 | cell division cycle 20 |
CDC6 | cell division cycle 6 |
CENPU | centromere protein U |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
CXCL11 | chemokine (C-X-C motif) ligand 11 |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
E2F2 | E2F transcription factor 2 |
ENO1 | enolase 1, (alpha) |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FABP7 | fatty acid binding protein 7, brain |
FOXM1 | forkhead box M1 |
GALE | UDP-galactose-4-epimerase |
GBP1 | guanylate binding protein 1, interferon-inducible |
GOLT1B | golgi transport 1B |
GPM6B | glycoprotein M6B |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
LMNB1 | lamin B1 |
MCM4 | minichromosome maintenance complex component 4 |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
MMP12 | matrix metallopeptidase 12 |
MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
NLRP2 | NLR family, pyrin domain containing 2 |
NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
RECQL | RecQ helicase-like |
RFC2 | replication factor C (activator 1) 2, 40kDa |
RFC4 | replication factor C (activator 1) 4, 37kDa |
RRM1 | ribonucleotide reductase M1 |
RRM2 | ribonucleotide reductase M2 |
SFRP1 | secreted frizzled-related protein 1 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
TYMS | thymidylate synthetase |
WARS | tryptophanyl-tRNA synthetase |
XIST | X inactive specific transcript (non-protein coding) |
ZWINT | ZW10 interacting kinetochore protein |