BRD-A87719232_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-A87719232_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AUTS2 autism susceptibility candidate 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLCA2 chloride channel accessory 2
COL3A1 collagen, type III, alpha 1
COL4A5 collagen, type IV, alpha 5
CSTA cystatin A (stefin A)
CYB5A cytochrome b5 type A (microsomal)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GUSBP3 glucuronidase, beta pseudogene 3
HILPDA hypoxia inducible lipid droplet-associated
HIST1H1C histone cluster 1, H1c
HOPX HOP homeobox
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IFITM1 interferon induced transmembrane protein 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0125 KIAA0125
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LOX lysyl oxidase
LPAR1 lysophosphatidic acid receptor 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NXN nucleoredoxin
PERP PERP, TP53 apoptosis effector
PLK2 polo-like kinase 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PXDN peroxidasin
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBPMS RNA binding protein with multiple splicing
RGS2 regulator of G-protein signaling 2
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLPI secretory leukocyte peptidase inhibitor
SPON1 spondin 1, extracellular matrix protein
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SSBP2 single-stranded DNA binding protein 2
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPM2 tropomyosin 2 (beta)
TPM4 tropomyosin 4
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADGRG6 adhesion G protein-coupled receptor G6
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ASCL1 achaete-scute family bHLH transcription factor 1
BTG2 BTG family, member 2
CCDC47 coiled-coil domain containing 47
CCL20 chemokine (C-C motif) ligand 20
CFD complement factor D (adipsin)
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP1 cysteine and glycine-rich protein 1
ELF1 E74-like factor 1 (ets domain transcription factor)
FAM107A family with sequence similarity 107, member A
GPM6B glycoprotein M6B
ICAM2 intercellular adhesion molecule 2
IGF1R insulin-like growth factor 1 receptor
IL6ST interleukin 6 signal transducer
KIAA1033 KIAA1033
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGALS4 lectin, galactoside-binding, soluble, 4
MSMB microseminoprotein, beta-
NGRN neugrin, neurite outgrowth associated
OLFM4 olfactomedin 4
PKN2 protein kinase N2
PPAP2B phosphatidic acid phosphatase type 2B
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SPINK1 serine peptidase inhibitor, Kazal type 1
SRGN serglycin
SRPX sushi-repeat containing protein, X-linked
TFF1 trefoil factor 1
TPR translocated promoter region, nuclear basket protein
Funding