BRD-A89333723_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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53 genes differentially expressed following the BRD-A89333723_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
CA1 carbonic anhydrase I
CD14 CD14 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
COLEC12 collectin sub-family member 12
CXCL10 chemokine (C-X-C motif) ligand 10
EZR ezrin
FASN fatty acid synthase
FRY furry homolog (Drosophila)
G6PD glucose-6-phosphate dehydrogenase
GAL galanin/GMAP prepropeptide
GRIA2 glutamate receptor, ionotropic, AMPA 2
GUSBP11 glucuronidase, beta pseudogene 11
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMG20B high mobility group 20B
IGL immunoglobulin lambda locus
LGALS8 lectin, galactoside-binding, soluble, 8
MEX3D mex-3 RNA binding family member D
MTA1 metastasis associated 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
CCL20 chemokine (C-C motif) ligand 20
CLDN10 claudin 10
CNIH1 cornichon family AMPA receptor auxiliary protein 1
COX11 COX11 cytochrome c oxidase copper chaperone
DDAH1 dimethylarginine dimethylaminohydrolase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EPCAM epithelial cell adhesion molecule
FAM171A1 family with sequence similarity 171, member A1
GPM6B glycoprotein M6B
GTF3A general transcription factor IIIA
HIST1H4C histone cluster 1, H4c
HPRT1 hypoxanthine phosphoribosyltransferase 1
IL1R1 interleukin 1 receptor, type I
ITGAV integrin, alpha V
LYPLA1 lysophospholipase I
NQO1 NAD(P)H dehydrogenase, quinone 1
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PTX3 pentraxin 3, long
RPS11 ribosomal protein S11
RPS27L ribosomal protein S27-like
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRY2 sprouty homolog 2 (Drosophila)
TOB1 transducer of ERBB2, 1
TSPYL5 TSPY-like 5
TXNDC9 thioredoxin domain containing 9
ZBTB18 zinc finger and BTB domain containing 18