BRD-A89337244_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-A89337244_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKRD10 ankyrin repeat domain 10
ANXA3 annexin A3
BASP1 brain abundant, membrane attached signal protein 1
CAV1 caveolin 1, caveolae protein, 22kDa
CD44 CD44 molecule (Indian blood group)
CD58 CD58 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CST3 cystatin C
CSTA cystatin A (stefin A)
CTSH cathepsin H
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
DHCR7 7-dehydrocholesterol reductase
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
ELOVL5 ELOVL fatty acid elongase 5
FABP4 fatty acid binding protein 4, adipocyte
FADS1 fatty acid desaturase 1
G0S2 G0/G1 switch 2
GDF15 growth differentiation factor 15
HACD1 3-hydroxyacyl-CoA dehydratase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP4 insulin-like growth factor binding protein 4
IGFBP7 insulin-like growth factor binding protein 7
IL1RN interleukin 1 receptor antagonist
INSIG1 insulin induced gene 1
KRT7 keratin 7, type II
LDLR low density lipoprotein receptor
LIPG lipase, endothelial
MACF1 microtubule-actin crosslinking factor 1
MSMO1 methylsterol monooxygenase 1
MTCL1 microtubule crosslinking factor 1
MYLK myosin light chain kinase
PRKCB protein kinase C, beta
RBP1 retinol binding protein 1, cellular
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SGK1 serum/glucocorticoid regulated kinase 1
SQLE squalene epoxidase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC2 stanniocalcin 2
TACSTD2 tumor-associated calcium signal transducer 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TP63 tumor protein p63
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
AKR1C1 aldo-keto reductase family 1, member C1
CA12 carbonic anhydrase XII
CLCA1 chloride channel accessory 1
GAS6 growth arrest-specific 6
HOXB2 homeobox B2
LPAR6 lysophosphatidic acid receptor 6
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NPTX2 neuronal pentraxin II
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
SDC2 syndecan 2
WDR61 WD repeat domain 61