| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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180 genes differentially expressed following the BRD-A94756469_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| ATF3 | activating transcription factor 3 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BTG2 | BTG family, member 2 |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CCNL1 | cyclin L1 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| COL11A1 | collagen, type XI, alpha 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTGF | connective tissue growth factor |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHCR24 | 24-dehydrocholesterol reductase |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EMP1 | epithelial membrane protein 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EZR | ezrin |
| FBN2 | fibrillin 2 |
| FOLR1 | folate receptor 1 (adult) |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL2 | FOS-like antigen 2 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATA6 | GATA binding protein 6 |
| GLS | glutaminase |
| H1F0 | H1 histone family, member 0 |
| HBB | hemoglobin, beta |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IER2 | immediate early response 2 |
| IER3 | immediate early response 3 |
| INSIG1 | insulin induced gene 1 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KDM5B | lysine (K)-specific demethylase 5B |
| KDM6B | lysine (K)-specific demethylase 6B |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF6 | Kruppel-like factor 6 |
| LRRC15 | leucine rich repeat containing 15 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAGEA3 | melanoma antigen family A3 |
| MCL1 | myeloid cell leukemia 1 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NET1 | neuroepithelial cell transforming 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUPL1 | nucleoporin like 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RGS1 | regulator of G-protein signaling 1 |
| RGS13 | regulator of G-protein signaling 13 |
| RGS2 | regulator of G-protein signaling 2 |
| RPL37A | ribosomal protein L37a |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SELENBP1 | selenium binding protein 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TFF3 | trefoil factor 3 (intestinal) |
| TFRC | transferrin receptor |
| THBS1 | thrombospondin 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSC22D2 | TSC22 domain family, member 2 |
| TSPAN13 | tetraspanin 13 |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| ZFP36 | ZFP36 ring finger protein |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ACD | adrenocortical dysplasia homolog (mouse) |
| ADCY1 | adenylate cyclase 1 (brain) |
| ADD3 | adducin 3 (gamma) |
| ADIRF | adipogenesis regulatory factor |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AIM1 | absent in melanoma 1 |
| ANXA4 | annexin A4 |
| APOD | apolipoprotein D |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATF5 | activating transcription factor 5 |
| ATMIN | ATM interactor |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BEX4 | brain expressed, X-linked 4 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C3 | complement component 3 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CBR1 | carbonyl reductase 1 |
| CBR3 | carbonyl reductase 3 |
| CCNA2 | cyclin A2 |
| CCND2 | cyclin D2 |
| CFB | complement factor B |
| CP | ceruloplasmin (ferroxidase) |
| CPE | carboxypeptidase E |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DEFB1 | defensin, beta 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DMXL1 | Dmx-like 1 |
| DPP4 | dipeptidyl-peptidase 4 |
| DUSP4 | dual specificity phosphatase 4 |
| FGB | fibrinogen beta chain |
| FN1 | fibronectin 1 |
| FRZB | frizzled-related protein |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GLRX | glutaredoxin (thioltransferase) |
| HGD | homogentisate 1,2-dioxygenase |
| HMGA2 | high mobility group AT-hook 2 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HRSP12 | heat-responsive protein 12 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA8 | heat shock 70kDa protein 8 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| IRS2 | insulin receptor substrate 2 |
| ITGA6 | integrin, alpha 6 |
| JADE2 | jade family PHD finger 2 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KLK3 | kallikrein-related peptidase 3 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MKKS | McKusick-Kaufman syndrome |
| MMP7 | matrix metallopeptidase 7 |
| MSLN | mesothelin |
| MSMB | microseminoprotein, beta- |
| MTDH | metadherin |
| NFIB | nuclear factor I/B |
| NMI | N-myc (and STAT) interactor |
| NPTXR | neuronal pentraxin receptor |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NRCAM | neuronal cell adhesion molecule |
| NUP62 | nucleoporin 62kDa |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| PURA | purine-rich element binding protein A |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
| SLC35E2B | solute carrier family 35, member E2B |
| SNX10 | sorting nexin 10 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPTSSA | serine palmitoyltransferase, small subunit A |
| TF | transferrin |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TJP2 | tight junction protein 2 |
| TMEM47 | transmembrane protein 47 |
| TMX4 | thioredoxin-related transmembrane protein 4 |
| TRAPPC3 | trafficking protein particle complex 3 |
| TRIM14 | tripartite motif containing 14 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
