BRD-A96485169_EBPC_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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83 genes differentially expressed following the BRD-A96485169_EBPC_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BAD BCL2-associated agonist of cell death
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CD14 CD14 molecule
CD24 CD24 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHGB chromogranin B
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN3 claudin 3
COG7 component of oligomeric golgi complex 7
CST1 cystatin SN
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FABP6 fatty acid binding protein 6, ileal
FGL2 fibrinogen-like 2
GCLC glutamate-cysteine ligase, catalytic subunit
HIST1H4C histone cluster 1, H4c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOPX HOP homeobox
IPO13 importin 13
KRT13 keratin 13, type I
KRT19 keratin 19, type I
KRT4 keratin 4, type II
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
NPIPB3 nuclear pore complex interacting protein family, member B3
PERP PERP, TP53 apoptosis effector
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMM2 phosphomannomutase 2
S100A8 S100 calcium binding protein A8
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
STAR steroidogenic acute regulatory protein
TLE4 transducin-like enhancer of split 4
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIM2 tripartite motif containing 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK4 adenylate kinase 4
ANGPTL2 angiopoietin-like 2
ANXA5 annexin A5
ARL4A ADP-ribosylation factor-like 4A
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
CDC42 cell division cycle 42
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYB5A cytochrome b5 type A (microsomal)
DARS aspartyl-tRNA synthetase
EGR3 early growth response 3
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOLR1 folate receptor 1 (adult)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GPM6B glycoprotein M6B
HAL histidine ammonia-lyase
HOMER1 homer scaffolding protein 1
IL6ST interleukin 6 signal transducer
KLF9 Kruppel-like factor 9
LMCD1 LIM and cysteine-rich domains 1
LPL lipoprotein lipase
MME membrane metallo-endopeptidase
PGC progastricsin (pepsinogen C)
PPARD peroxisome proliferator-activated receptor delta
PTPRO protein tyrosine phosphatase, receptor type, O
RHOB ras homolog family member B
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
SH3BP4 SH3-domain binding protein 4
SNX7 sorting nexin 7
SORD sorbitol dehydrogenase
SOX9 SRY (sex determining region Y)-box 9
TNS1 tensin 1
TWIST1 twist family bHLH transcription factor 1
TYRP1 tyrosinase-related protein 1
ZCCHC24 zinc finger, CCHC domain containing 24