Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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133 genes differentially expressed following the BRD-K00313977_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADGRF5 | adhesion G protein-coupled receptor F5 |
AKAP8L | A kinase (PRKA) anchor protein 8-like |
ANOS1 | anosmin 1 |
APLP2 | amyloid beta (A4) precursor-like protein 2 |
APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
AREG | amphiregulin |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
BASP1 | brain abundant, membrane attached signal protein 1 |
BAX | BCL2-associated X protein |
BSG | basigin (Ok blood group) |
CDK19 | cyclin-dependent kinase 19 |
CKM | creatine kinase, muscle |
COCH | cochlin |
CPM | carboxypeptidase M |
CSNK2A2 | casein kinase 2, alpha prime polypeptide |
CTGF | connective tissue growth factor |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DUSP1 | dual specificity phosphatase 1 |
DUSP10 | dual specificity phosphatase 10 |
DUSP4 | dual specificity phosphatase 4 |
EGR2 | early growth response 2 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
FOSL1 | FOS-like antigen 1 |
FOXO1 | forkhead box O1 |
FZD7 | frizzled class receptor 7 |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GPM6A | glycoprotein M6A |
H3F3B | H3 histone, family 3B (H3.3B) |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
ICAM1 | intercellular adhesion molecule 1 |
IFT57 | intraflagellar transport 57 |
KDM3A | lysine (K)-specific demethylase 3A |
KDM5B | lysine (K)-specific demethylase 5B |
KLK11 | kallikrein-related peptidase 11 |
LAMP3 | lysosomal-associated membrane protein 3 |
LPIN2 | lipin 2 |
LSR | lipolysis stimulated lipoprotein receptor |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAOA | monoamine oxidase A |
MARK4 | MAP/microtubule affinity-regulating kinase 4 |
MCL1 | myeloid cell leukemia 1 |
NID1 | nidogen 1 |
NT5E | 5'-nucleotidase, ecto (CD73) |
PDGFA | platelet-derived growth factor alpha polypeptide |
PEG10 | paternally expressed 10 |
PERP | PERP, TP53 apoptosis effector |
PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha |
RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
RGCC | regulator of cell cycle |
RGS2 | regulator of G-protein signaling 2 |
RRAD | Ras-related associated with diabetes |
SESN1 | sestrin 1 |
SFTPB | surfactant protein B |
SORBS1 | sorbin and SH3 domain containing 1 |
SUN1 | Sad1 and UNC84 domain containing 1 |
TDO2 | tryptophan 2,3-dioxygenase |
TKTL1 | transketolase-like 1 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
TPM4 | tropomyosin 4 |
TSPAN12 | tetraspanin 12 |
UBE3B | ubiquitin protein ligase E3B |
WAC | WW domain containing adaptor with coiled-coil |
YBX3 | Y box binding protein 3 |
YES1 | YES proto-oncogene 1, Src family tyrosine kinase |
ZDHHC11 | zinc finger, DHHC-type containing 11 |
Symbol | Name |
---|---|
ADD3 | adducin 3 (gamma) |
ADIRF | adipogenesis regulatory factor |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ANXA10 | annexin A10 |
APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 |
AUTS2 | autism susceptibility candidate 2 |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CFD | complement factor D (adipsin) |
CTBP2 | C-terminal binding protein 2 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
DCK | deoxycytidine kinase |
DDIT4 | DNA-damage-inducible transcript 4 |
DENND2D | DENN/MADD domain containing 2D |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
EIF4B | eukaryotic translation initiation factor 4B |
EIF5 | eukaryotic translation initiation factor 5 |
FCGBP | Fc fragment of IgG binding protein |
GABPB1 | GA binding protein transcription factor, beta subunit 1 |
GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
GOLGA8H | golgin A8 family, member H |
HIST1H2AC | histone cluster 1, H2ac |
HIST1H2BG | histone cluster 1, H2bg |
HOXA5 | homeobox A5 |
HOXC6 | homeobox C6 |
HSPA8 | heat shock 70kDa protein 8 |
KIF14 | kinesin family member 14 |
KLHL9 | kelch-like family member 9 |
KRT19 | keratin 19, type I |
LRRC16A | leucine rich repeat containing 16A |
LYZ | lysozyme |
MAT2A | methionine adenosyltransferase II, alpha |
MATN2 | matrilin 2 |
METTL7A | methyltransferase like 7A |
MT1F | metallothionein 1F |
MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NDE1 | nudE neurodevelopment protein 1 |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
OLFML3 | olfactomedin-like 3 |
PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
PROM1 | prominin 1 |
PRR15L | proline rich 15-like |
PSCA | prostate stem cell antigen |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
RPL10 | ribosomal protein L10 |
S100A6 | S100 calcium binding protein A6 |
SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 |
SORD | sorbitol dehydrogenase |
SRSF7 | serine/arginine-rich splicing factor 7 |
TMEM97 | transmembrane protein 97 |
TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 |
TP53I3 | tumor protein p53 inducible protein 3 |
TPD52L1 | tumor protein D52-like 1 |
TSKU | tsukushi, small leucine rich proteoglycan |
TUSC3 | tumor suppressor candidate 3 |
UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
VCAM1 | vascular cell adhesion molecule 1 |
XBP1 | X-box binding protein 1 |
ZDHHC6 | zinc finger, DHHC-type containing 6 |