BRD-K00337317_NU-7441_HS578T_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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83 genes differentially expressed following the BRD-K00337317_NU-7441_HS578T_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ASCL1 achaete-scute family bHLH transcription factor 1
ASPN asporin
BST2 bone marrow stromal cell antigen 2
CCDC85B coiled-coil domain containing 85B
CDC14B cell division cycle 14B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC2B C-type lectin domain family 2, member B
DHCR24 24-dehydrocholesterol reductase
ETV1 ets variant 1
FABP4 fatty acid binding protein 4, adipocyte
FBLN1 fibulin 1
FOXO4 forkhead box O4
HLA-C major histocompatibility complex, class I, C
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IGHMBP2 immunoglobulin mu binding protein 2
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LUM lumican
LY96 lymphocyte antigen 96
NCOA3 nuclear receptor coactivator 3
PDGFD platelet derived growth factor D
PEG10 paternally expressed 10
RBP1 retinol binding protein 1, cellular
SEPP1 selenoprotein P, plasma, 1
SFTPB surfactant protein B
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SOX4 SRY (sex determining region Y)-box 4
STXBP1 syntaxin binding protein 1
THBS2 thrombospondin 2
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSC22D1 TSC22 domain family, member 1

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADGRG6 adhesion G protein-coupled receptor G6
BIRC2 baculoviral IAP repeat containing 2
CAPN6 calpain 6
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CENPU centromere protein U
CPM carboxypeptidase M
CSRP1 cysteine and glycine-rich protein 1
CSTA cystatin A (stefin A)
CTPS1 CTP synthase 1
DES desmin
DLD dihydrolipoamide dehydrogenase
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DNM1L dynamin 1-like
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F2 E2F transcription factor 2
EMX2 empty spiracles homeobox 2
ENO1 enolase 1, (alpha)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM129A family with sequence similarity 129, member A
FEN1 flap structure-specific endonuclease 1
FGFR2 fibroblast growth factor receptor 2
GINS1 GINS complex subunit 1 (Psf1 homolog)
GLIPR1 GLI pathogenesis-related 1
HELLS helicase, lymphoid-specific
HSPD1 heat shock 60kDa protein 1 (chaperonin)
KIAA0226L KIAA0226-like
KRT81 keratin 81, type II
LDHB lactate dehydrogenase B
LRRC59 leucine rich repeat containing 59
LTF lactotransferrin
MAP7 microtubule-associated protein 7
MCM2 minichromosome maintenance complex component 2
NEFL neurofilament, light polypeptide
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PSCA prostate stem cell antigen
RRM2 ribonucleotide reductase M2
S100P S100 calcium binding protein P
SLN sarcolipin
TPM1 tropomyosin 1 (alpha)
TYMS thymidylate synthetase
ZWINT ZW10 interacting kinetochore protein