BRD-K00366212_2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-8-methoxyquinazolin-4-amine KUC106573N_HT29_6.0_h_10.0_um Gene Set
Genes
25 genes differentially expressed following the BRD-K00366212_2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-8-methoxyquinazolin-4-amine KUC106573N_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
AKR1C2
|
aldo-keto reductase family 1, member C2
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
|
CHI3L2
|
chitinase 3-like 2
|
|
IKBKAP
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
|
|
IMPA2
|
inositol(myo)-1(or 4)-monophosphatase 2
|
|
PMP22
|
peripheral myelin protein 22
|
|
SLC16A1
|
solute carrier family 16 (monocarboxylate transporter), member 1
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
|
TBC1D31
|
TBC1 domain family, member 31
|
|
TNFSF10
|
tumor necrosis factor (ligand) superfamily, member 10
|
|
TPD52L1
|
tumor protein D52-like 1
|
|
TRIB2
|
tribbles pseudokinase 2
|
decreased expression
| Symbol |
Name |
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
|
CCND2
|
cyclin D2
|
|
DKK3
|
dickkopf WNT signaling pathway inhibitor 3
|
|
F2RL1
|
coagulation factor II (thrombin) receptor-like 1
|
|
FILIP1L
|
filamin A interacting protein 1-like
|
|
HLA-DQB1
|
major histocompatibility complex, class II, DQ beta 1
|
|
MDK
|
midkine (neurite growth-promoting factor 2)
|
|
MSLN
|
mesothelin
|
|
NT5E
|
5'-nucleotidase, ecto (CD73)
|
|
PRG2
|
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
|
|
RAPGEF5
|
Rap guanine nucleotide exchange factor (GEF) 5
|
|
RTN1
|
reticulon 1
|
|
SPINK1
|
serine peptidase inhibitor, Kazal type 1
|
