Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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62 genes differentially expressed following the BRD-K00555438_2-Phenyl-quinoline-4-carboxylic acid [4-(thiazol-2-ylsulfamoyl)-phenyl]-amide MLS-0206672.0001_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C2 | aldo-keto reductase family 1, member C2 |
ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
CA12 | carbonic anhydrase XII |
CCL4 | chemokine (C-C motif) ligand 4 |
CCL5 | chemokine (C-C motif) ligand 5 |
CDKN2A | cyclin-dependent kinase inhibitor 2A |
CFLAR | CASP8 and FADD-like apoptosis regulator |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CSTA | cystatin A (stefin A) |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
DST | dystonin |
EIF5A | eukaryotic translation initiation factor 5A |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
EPAS1 | endothelial PAS domain protein 1 |
GCLC | glutamate-cysteine ligase, catalytic subunit |
GCLM | glutamate-cysteine ligase, modifier subunit |
GLUL | glutamate-ammonia ligase |
GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
HLX | H2.0-like homeobox |
HMOX1 | heme oxygenase 1 |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MMP12 | matrix metallopeptidase 12 |
NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
NGRN | neugrin, neurite outgrowth associated |
PTN | pleiotrophin |
S100A2 | S100 calcium binding protein A2 |
SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
TMEM47 | transmembrane protein 47 |
VAV3 | vav 3 guanine nucleotide exchange factor |
Symbol | Name |
---|---|
ADGRG2 | adhesion G protein-coupled receptor G2 |
ALB | albumin |
APOD | apolipoprotein D |
AREG | amphiregulin |
ARHGAP29 | Rho GTPase activating protein 29 |
CRISP3 | cysteine-rich secretory protein 3 |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
GLIPR1 | GLI pathogenesis-related 1 |
HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
IGFBP1 | insulin-like growth factor binding protein 1 |
IRS1 | insulin receptor substrate 1 |
KRT23 | keratin 23, type I |
KRT8 | keratin 8, type II |
NT5E | 5'-nucleotidase, ecto (CD73) |
PDGFC | platelet derived growth factor C |
PLAT | plasminogen activator, tissue |
PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
RCAN1 | regulator of calcineurin 1 |
S100P | S100 calcium binding protein P |
SKAP2 | src kinase associated phosphoprotein 2 |
SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
TFF1 | trefoil factor 1 |
THBS1 | thrombospondin 1 |
THBS2 | thrombospondin 2 |
TOB1 | transducer of ERBB2, 1 |