BRD-K00610438_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K00610438_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA4 annexin A4
BEX1 brain expressed, X-linked 1
CAB39 calcium binding protein 39
CCL19 chemokine (C-C motif) ligand 19
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTSZ cathepsin Z
DUSP4 dual specificity phosphatase 4
FHL1 four and a half LIM domains 1
G0S2 G0/G1 switch 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GSTO1 glutathione S-transferase omega 1
HBD hemoglobin, delta
HEPH hephaestin
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
IQGAP2 IQ motif containing GTPase activating protein 2
LDHB lactate dehydrogenase B
LGALS1 lectin, galactoside-binding, soluble, 1
LIPG lipase, endothelial
LXN latexin
MACF1 microtubule-actin crosslinking factor 1
MAGED1 melanoma antigen family D1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MFAP5 microfibrillar associated protein 5
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NME4 NME/NM23 nucleoside diphosphate kinase 4
PDLIM1 PDZ and LIM domain 1
PLAC8 placenta-specific 8
PLCB4 phospholipase C, beta 4
PPIC peptidylprolyl isomerase C (cyclophilin C)
RGS5 regulator of G-protein signaling 5
SQLE squalene epoxidase
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TCF4 transcription factor 4
VIM vimentin
XK X-linked Kx blood group

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AQP3 aquaporin 3 (Gill blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASS1 argininosuccinate synthase 1
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BCL6 B-cell CLL/lymphoma 6
BPHL biphenyl hydrolase-like (serine hydrolase)
CFI complement factor I
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CP ceruloplasmin (ferroxidase)
CRABP2 cellular retinoic acid binding protein 2
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENO1 enolase 1, (alpha)
EXT1 exostosin glycosyltransferase 1
GJA1 gap junction protein, alpha 1, 43kDa
GRB7 growth factor receptor-bound protein 7
GUSBP11 glucuronidase, beta pseudogene 11
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
ITM2B integral membrane protein 2B
KIF20A kinesin family member 20A
KRT13 keratin 13, type I
KRT4 keratin 4, type II
LPAR6 lysophosphatidic acid receptor 6
MCL1 myeloid cell leukemia 1
MSLN mesothelin
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NELL2 NEL-like 2 (chicken)
NR4A2 nuclear receptor subfamily 4, group A, member 2
PEG10 paternally expressed 10
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
RGCC regulator of cell cycle
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDC2 syndecan 2
SELENBP1 selenium binding protein 1
SHB Src homology 2 domain containing adaptor protein B
SLPI secretory leukocyte peptidase inhibitor
SNX7 sorting nexin 7
STC1 stanniocalcin 1
TACSTD2 tumor-associated calcium signal transducer 2