Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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78 genes differentially expressed following the BRD-K01436366_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACAA1 | acetyl-CoA acyltransferase 1 |
ALOX15B | arachidonate 15-lipoxygenase, type B |
APLP2 | amyloid beta (A4) precursor-like protein 2 |
C3ORF14 | chromosome 3 open reading frame 14 |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
CCNG2 | cyclin G2 |
CD24 | CD24 molecule |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CNTNAP2 | contactin associated protein-like 2 |
COL11A1 | collagen, type XI, alpha 1 |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
CYB5R1 | cytochrome b5 reductase 1 |
CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
H2BFS | H2B histone family, member S (pseudogene) |
HIST1H2BK | histone cluster 1, H2bk |
HK1 | hexokinase 1 |
HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
KLK6 | kallikrein-related peptidase 6 |
KRT7 | keratin 7, type II |
LAMP2 | lysosomal-associated membrane protein 2 |
MAP7 | microtubule-associated protein 7 |
MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
NEBL | nebulette |
NMU | neuromedin U |
NSDHL | NAD(P) dependent steroid dehydrogenase-like |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PSAP | prosaposin |
RYBP | RING1 and YY1 binding protein |
S100A8 | S100 calcium binding protein A8 |
S100A9 | S100 calcium binding protein A9 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
SGK1 | serum/glucocorticoid regulated kinase 1 |
SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
STXBP1 | syntaxin binding protein 1 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TMEM165 | transmembrane protein 165 |
TST | thiosulfate sulfurtransferase (rhodanese) |
YPEL5 | yippee-like 5 (Drosophila) |
Symbol | Name |
---|---|
ACTN1 | actinin, alpha 1 |
ATF3 | activating transcription factor 3 |
CASP7 | caspase 7, apoptosis-related cysteine peptidase |
CCDC86 | coiled-coil domain containing 86 |
CD44 | CD44 molecule (Indian blood group) |
COL6A2 | collagen, type VI, alpha 2 |
COL6A3 | collagen, type VI, alpha 3 |
CP | ceruloplasmin (ferroxidase) |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FCGBP | Fc fragment of IgG binding protein |
FHL2 | four and a half LIM domains 2 |
FOSL1 | FOS-like antigen 1 |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HOXB7 | homeobox B7 |
HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
LAMC1 | laminin, gamma 1 (formerly LAMB2) |
MECOM | MDS1 and EVI1 complex locus |
MSX1 | msh homeobox 1 |
NMI | N-myc (and STAT) interactor |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PRAME | preferentially expressed antigen in melanoma |
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
REG1A | regenerating islet-derived 1 alpha |
RPIA | ribose 5-phosphate isomerase A |
RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
S100P | S100 calcium binding protein P |
SORBS3 | sorbin and SH3 domain containing 3 |
SPATS2L | spermatogenesis associated, serine-rich 2-like |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
ZIC1 | Zic family member 1 |