BRD-K01578344_-666_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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72 genes differentially expressed following the BRD-K01578344_-666_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
CCND1 cyclin D1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
FZD7 frizzled class receptor 7
GAL galanin/GMAP prepropeptide
HBB hemoglobin, beta
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IL1R2 interleukin 1 receptor, type II
KRT14 keratin 14, type I
KRT17 keratin 17, type I
MYO6 myosin VI
MZT2A mitotic spindle organizing protein 2A
NELL2 NEL-like 2 (chicken)
NT5DC2 5'-nucleotidase domain containing 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OXTR oxytocin receptor
PROM1 prominin 1
RBP4 retinol binding protein 4, plasma
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDC4 syndecan 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SOX9 SRY (sex determining region Y)-box 9
TXNIP thioredoxin interacting protein
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
C7 complement component 7
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALD1 caldesmon 1
CD24 CD24 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CHRDL1 chordin-like 1
CYCS cytochrome c, somatic
DCN decorin
EHF ets homologous factor
EIF5 eukaryotic translation initiation factor 5
FBLN1 fibulin 1
HES1 hes family bHLH transcription factor 1
HOPX HOP homeobox
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGLJ3 immunoglobulin lambda joining 3
IL1R1 interleukin 1 receptor, type I
KLK11 kallikrein-related peptidase 11
LMO2 LIM domain only 2 (rhombotin-like 1)
MNS1 meiosis-specific nuclear structural 1
MSMB microseminoprotein, beta-
MYH11 myosin, heavy chain 11, smooth muscle
NR4A2 nuclear receptor subfamily 4, group A, member 2
PCP4 Purkinje cell protein 4
PLN phospholamban
POU2AF1 POU class 2 associating factor 1
PPIC peptidylprolyl isomerase C (cyclophilin C)
PTGDS prostaglandin D2 synthase 21kDa (brain)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A8 S100 calcium binding protein A8
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFRP4 secreted frizzled-related protein 4
SOX4 SRY (sex determining region Y)-box 4
TSPAN8 tetraspanin 8
TUBB2A tubulin, beta 2A class IIa
ZFPM2 zinc finger protein, FOG family member 2