BRD-K01834163_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K01834163_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
GLUL glutamate-ammonia ligase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
KYNU kynureninase
MMP7 matrix metallopeptidase 7
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCSK6 proprotein convertase subtilisin/kexin type 6
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SOD2 superoxide dismutase 2, mitochondrial
SQSTM1 sequestosome 1
SST somatostatin
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ANXA3 annexin A3
CCND1 cyclin D1
CELF2 CUGBP, Elav-like family member 2
DAPK1 death-associated protein kinase 1
FLNB filamin B, beta
GPRC5A G protein-coupled receptor, class C, group 5, member A
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MX2 MX dynamin-like GTPase 2
SFRP1 secreted frizzled-related protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRPX sushi-repeat containing protein, X-linked
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TSPAN13 tetraspanin 13