Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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68 genes differentially expressed following the BRD-K01868942_3-(piperidin-1-yl)propyl-4-amino-5-chloro-2methoxybenzoate . Hydrochloride_VCAP_24.0_h_160.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACTN1 | actinin, alpha 1 |
AGTR1 | angiotensin II receptor, type 1 |
AIM1 | absent in melanoma 1 |
ANKRD10 | ankyrin repeat domain 10 |
APOD | apolipoprotein D |
C16ORF45 | chromosome 16 open reading frame 45 |
CCNG2 | cyclin G2 |
CDK19 | cyclin-dependent kinase 19 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
DDIT4 | DNA-damage-inducible transcript 4 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DHCR24 | 24-dehydrocholesterol reductase |
DHCR7 | 7-dehydrocholesterol reductase |
FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
FGF13 | fibroblast growth factor 13 |
FOXO4 | forkhead box O4 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
INSIG1 | insulin induced gene 1 |
LDLR | low density lipoprotein receptor |
LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
MARCKSL1 | MARCKS-like 1 |
MSMO1 | methylsterol monooxygenase 1 |
PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
SC5D | sterol-C5-desaturase |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SERINC5 | serine incorporator 5 |
SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
SQLE | squalene epoxidase |
TFF1 | trefoil factor 1 |
UGCG | UDP-glucose ceramide glucosyltransferase |
Symbol | Name |
---|---|
BZW2 | basic leucine zipper and W2 domains 2 |
C1QA | complement component 1, q subcomponent, A chain |
CDC25A | cell division cycle 25A |
CDC45 | cell division cycle 45 |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
EGFR | epidermal growth factor receptor |
EIF5A | eukaryotic translation initiation factor 5A |
FGFR3 | fibroblast growth factor receptor 3 |
GSTP1 | glutathione S-transferase pi 1 |
GUSBP11 | glucuronidase, beta pseudogene 11 |
HHEX | hematopoietically expressed homeobox |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
HOPX | HOP homeobox |
HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
IGHM | immunoglobulin heavy constant mu |
IGKC | immunoglobulin kappa constant |
IGKV1-5 | immunoglobulin kappa variable 1-5 |
IGL | immunoglobulin lambda locus |
IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
MCM2 | minichromosome maintenance complex component 2 |
MCM3 | minichromosome maintenance complex component 3 |
MCM4 | minichromosome maintenance complex component 4 |
MCM5 | minichromosome maintenance complex component 5 |
MT1E | metallothionein 1E |
POSTN | periostin, osteoblast specific factor |
RRM2 | ribonucleotide reductase M2 |
TMEM176B | transmembrane protein 176B |
WARS | tryptophanyl-tRNA synthetase |
XIST | X inactive specific transcript (non-protein coding) |