Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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71 genes differentially expressed following the BRD-K02113016_olaparib_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACSL1 | acyl-CoA synthetase long-chain family member 1 |
ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
ADIPOQ | adiponectin, C1Q and collagen domain containing |
AKR1C1 | aldo-keto reductase family 1, member C1 |
ANXA4 | annexin A4 |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
AUTS2 | autism susceptibility candidate 2 |
CD24 | CD24 molecule |
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
FLNB | filamin B, beta |
GDF15 | growth differentiation factor 15 |
GSN | gelsolin |
GSTP1 | glutathione S-transferase pi 1 |
HBE1 | hemoglobin, epsilon 1 |
HOOK2 | hook microtubule-tethering protein 2 |
HOXC10 | homeobox C10 |
KANK1 | KN motif and ankyrin repeat domains 1 |
KRT16 | keratin 16, type I |
KRT17 | keratin 17, type I |
KRT18 | keratin 18, type I |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
PPL | periplakin |
RAB38 | RAB38, member RAS oncogene family |
RBP4 | retinol binding protein 4, plasma |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SOX9 | SRY (sex determining region Y)-box 9 |
VDAC1 | voltage-dependent anion channel 1 |
Symbol | Name |
---|---|
AGTR1 | angiotensin II receptor, type 1 |
AREG | amphiregulin |
CCNB1 | cyclin B1 |
CCNE2 | cyclin E2 |
COL6A2 | collagen, type VI, alpha 2 |
CP | ceruloplasmin (ferroxidase) |
CRELD2 | cysteine-rich with EGF-like domains 2 |
CTGF | connective tissue growth factor |
DCN | decorin |
EBP | emopamil binding protein (sterol isomerase) |
FBXL12 | F-box and leucine-rich repeat protein 12 |
FCGBP | Fc fragment of IgG binding protein |
FOLR1 | folate receptor 1 (adult) |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
IFI27 | interferon, alpha-inducible protein 27 |
IFI44 | interferon-induced protein 44 |
IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
ISG15 | ISG15 ubiquitin-like modifier |
MT1E | metallothionein 1E |
MT1F | metallothionein 1F |
MT1G | metallothionein 1G |
MT1H | metallothionein 1H |
MT1HL1 | metallothionein 1H-like 1 |
MT1M | metallothionein 1M |
MT1X | metallothionein 1X |
MT2A | metallothionein 2A |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
PPIC | peptidylprolyl isomerase C (cyclophilin C) |
PPIF | peptidylprolyl isomerase F |
PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
PUF60 | poly-U binding splicing factor 60KDa |
RND3 | Rho family GTPase 3 |
RRM2 | ribonucleotide reductase M2 |
SGCE | sarcoglycan, epsilon |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
SPON2 | spondin 2, extracellular matrix protein |
SPRED2 | sprouty-related, EVH1 domain containing 2 |
STK10 | serine/threonine kinase 10 |
VCAN | versican |