BRD-K02562327_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K02562327_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA4 annexin A4
ARG2 arginase 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CD9 CD9 molecule
CD93 CD93 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FAM69A family with sequence similarity 69, member A
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
KRT18 keratin 18, type I
KRT19 keratin 19, type I
LYZ lysozyme
MXRA7 matrix-remodelling associated 7
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RHOB ras homolog family member B
SMAD3 SMAD family member 3
THBS2 thrombospondin 2
TMSB15A thymosin beta 15a
VWF von Willebrand factor

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CHL1 cell adhesion molecule L1-like
COL1A2 collagen, type I, alpha 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
HSPA1A heat shock 70kDa protein 1A
KIF14 kinesin family member 14
MMP12 matrix metallopeptidase 12
MRPS2 mitochondrial ribosomal protein S2
PAEP progestagen-associated endometrial protein
TNPO1 transportin 1