Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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125 genes differentially expressed following the BRD-K02590140_O-2050_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
ADAM9 | ADAM metallopeptidase domain 9 |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
C1QA | complement component 1, q subcomponent, A chain |
C5AR1 | complement component 5a receptor 1 |
CA1 | carbonic anhydrase I |
CA12 | carbonic anhydrase XII |
CD14 | CD14 molecule |
CD151 | CD151 molecule (Raph blood group) |
CRABP2 | cellular retinoic acid binding protein 2 |
CST7 | cystatin F (leukocystatin) |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DDR1 | discoidin domain receptor tyrosine kinase 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DUSP14 | dual specificity phosphatase 14 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
FBN2 | fibrillin 2 |
FKBP11 | FK506 binding protein 11, 19 kDa |
FLOT1 | flotillin 1 |
GLRX | glutaredoxin (thioltransferase) |
GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
GSTA4 | glutathione S-transferase alpha 4 |
HIST1H1C | histone cluster 1, H1c |
HIST1H2BK | histone cluster 1, H2bk |
HMOX1 | heme oxygenase 1 |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
IGKC | immunoglobulin kappa constant |
INHBB | inhibin, beta B |
KDM5D | lysine (K)-specific demethylase 5D |
LGALS8 | lectin, galactoside-binding, soluble, 8 |
MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
MEX3D | mex-3 RNA binding family member D |
NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
PAIP1 | poly(A) binding protein interacting protein 1 |
PCGF2 | polycomb group ring finger 2 |
PTN | pleiotrophin |
RGCC | regulator of cell cycle |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
RXRA | retinoid X receptor, alpha |
S100A2 | S100 calcium binding protein A2 |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
SOX11 | SRY (sex determining region Y)-box 11 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TRIP6 | thyroid hormone receptor interactor 6 |
USP18 | ubiquitin specific peptidase 18 |
VEGFA | vascular endothelial growth factor A |
VSIG4 | V-set and immunoglobulin domain containing 4 |
ZIC1 | Zic family member 1 |
Symbol | Name |
---|---|
ACTN1 | actinin, alpha 1 |
ADD3 | adducin 3 (gamma) |
AHR | aryl hydrocarbon receptor |
ALB | albumin |
AZIN1 | antizyme inhibitor 1 |
BEX1 | brain expressed, X-linked 1 |
C6ORF62 | chromosome 6 open reading frame 62 |
C7 | complement component 7 |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
COL14A1 | collagen, type XIV, alpha 1 |
COL1A1 | collagen, type I, alpha 1 |
COLEC11 | collectin sub-family member 11 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CYBA | cytochrome b-245, alpha polypeptide |
CYCS | cytochrome c, somatic |
DCN | decorin |
DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
DLC1 | DLC1 Rho GTPase activating protein |
DUSP22 | dual specificity phosphatase 22 |
DUSP3 | dual specificity phosphatase 3 |
EIF5 | eukaryotic translation initiation factor 5 |
ELF1 | E74-like factor 1 (ets domain transcription factor) |
F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
FGFR2 | fibroblast growth factor receptor 2 |
FHL1 | four and a half LIM domains 1 |
FN1 | fibronectin 1 |
GPC3 | glypican 3 |
HIST1H2BG | histone cluster 1, H2bg |
HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
HSPA8 | heat shock 70kDa protein 8 |
IL6ST | interleukin 6 signal transducer |
ISL1 | ISL LIM homeobox 1 |
KAT6B | K(lysine) acetyltransferase 6B |
LAMP5 | lysosomal-associated membrane protein family, member 5 |
LYZ | lysozyme |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MATN2 | matrilin 2 |
MBNL1 | muscleblind-like splicing regulator 1 |
MGP | matrix Gla protein |
NOTCH2NL | notch 2 N-terminal like |
OPN3 | opsin 3 |
P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
PLK2 | polo-like kinase 2 |
PPIF | peptidylprolyl isomerase F |
PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
PRPS2 | phosphoribosyl pyrophosphate synthetase 2 |
PRSS3 | protease, serine, 3 |
PSPH | phosphoserine phosphatase |
PTP4A2 | protein tyrosine phosphatase type IVA, member 2 |
RGS4 | regulator of G-protein signaling 4 |
RPL27A | ribosomal protein L27a |
RPL37A | ribosomal protein L37a |
RPL38 | ribosomal protein L38 |
RPS11 | ribosomal protein S11 |
SCYL3 | SCY1-like 3 (S. cerevisiae) |
SKAP2 | src kinase associated phosphoprotein 2 |
SLC38A2 | solute carrier family 38, member 2 |
SOX4 | SRY (sex determining region Y)-box 4 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
SRSF7 | serine/arginine-rich splicing factor 7 |
SST | somatostatin |
TFRC | transferrin receptor |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
THBS1 | thrombospondin 1 |
THBS2 | thrombospondin 2 |
TSPAN8 | tetraspanin 8 |
TXNIP | thioredoxin interacting protein |
VCL | vinculin |
XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |