BRD-K02708799_GSK-1059615_A375_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

530 genes differentially expressed following the BRD-K02708799_GSK-1059615_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AAMDC adipogenesis associated, Mth938 domain containing
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACVR1 activin A receptor, type I
ADCK3 aarF domain containing kinase 3
ADCY1 adenylate cyclase 1 (brain)
ADD3 adducin 3 (gamma)
AGTPBP1 ATP/GTP binding protein 1
AHNAK2 AHNAK nucleoprotein 2
ALDOA aldolase A, fructose-bisphosphate
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA4 annexin A4
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOL1 apolipoprotein L, 1
APOLD1 apolipoprotein L domain containing 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ASMTL acetylserotonin O-methyltransferase-like
ASS1 argininosuccinate synthase 1
ATM ATM serine/threonine kinase
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BAG6 BCL2-associated athanogene 6
BAX BCL2-associated X protein
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
BTBD3 BTB (POZ) domain containing 3
BTG1 B-cell translocation gene 1, anti-proliferative
C10ORF10 chromosome 10 open reading frame 10
C1RL complement component 1, r subcomponent-like
C4BPA complement component 4 binding protein, alpha
C6ORF48 chromosome 6 open reading frame 48
C9ORF16 chromosome 9 open reading frame 16
CALCOCO1 calcium binding and coiled-coil domain 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC92 coiled-coil domain containing 92
CCND2 cyclin D2
CCNG1 cyclin G1
CCNG2 cyclin G2
CCP110 centriolar coiled coil protein 110kDa
CCPG1 cell cycle progression 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD99 CD99 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK19 cyclin-dependent kinase 19
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEMIP cell migration inducing protein, hyaluronan binding
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIRBP cold inducible RNA binding protein
CKAP4 cytoskeleton-associated protein 4
CLEC11A C-type lectin domain family 11, member A
CLEC2B C-type lectin domain family 2, member B
CLNS1A chloride channel, nucleotide-sensitive, 1A
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CORO1A coronin, actin binding protein, 1A
CREB3L1 cAMP responsive element binding protein 3-like 1
CRISP3 cysteine-rich secretory protein 3
CSNK1D casein kinase 1, delta
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTSA cathepsin A
CTSK cathepsin K
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL5 chemokine (C-X-C motif) ligand 5
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DDR2 discoidin domain receptor tyrosine kinase 2
DEPTOR DEP domain containing MTOR-interacting protein
DHCR7 7-dehydrocholesterol reductase
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL3 dihydropyrimidinase-like 3
EFNB2 ephrin-B2
EIF4B eukaryotic translation initiation factor 4B
EMP1 epithelial membrane protein 1
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB3 erb-b2 receptor tyrosine kinase 3
ETV1 ets variant 1
F13A1 coagulation factor XIII, A1 polypeptide
F5 coagulation factor V (proaccelerin, labile factor)
FAM134B family with sequence similarity 134, member B
FAM46A family with sequence similarity 46, member A
FAM63A family with sequence similarity 63, member A
FGG fibrinogen gamma chain
FNBP1 formin binding protein 1
FOXN3 forkhead box N3
FOXO4 forkhead box O4
FZD6 frizzled class receptor 6
FZD7 frizzled class receptor 7
GAB2 GRB2-associated binding protein 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GAS6 growth arrest-specific 6
GBP2 guanylate binding protein 2, interferon-inducible
GLTSCR2 glioma tumor suppressor candidate region gene 2
GLUL glutamate-ammonia ligase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GOLGB1 golgin B1
GPATCH8 G patch domain containing 8
GPNMB glycoprotein (transmembrane) nmb
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSDMB gasdermin B
GSN gelsolin
GSTT1 glutathione S-transferase theta 1
GUSBP3 glucuronidase, beta pseudogene 3
GYG2 glycogenin 2
H2BFS H2B histone family, member S (pseudogene)
HCP5 HLA complex P5 (non-protein coding)
HDAC5 histone deacetylase 5
HDAC6 histone deacetylase 6
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HLA-B major histocompatibility complex, class I, B
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HOOK2 hook microtubule-tethering protein 2
IDS iduronate 2-sulfatase
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGBP1 immunoglobulin (CD79A) binding protein 1
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGHM immunoglobulin heavy constant mu
IGKV3-20 immunoglobulin kappa variable 3-20
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IRF9 interferon regulatory factor 9
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JARID2 jumonji, AT rich interactive domain 2
JUP junction plakoglobin
KCTD14 potassium channel tetramerization domain containing 14
KLF5 Kruppel-like factor 5 (intestinal)
KLK10 kallikrein-related peptidase 10
KRT19 keratin 19, type I
LAMP5 lysosomal-associated membrane protein family, member 5
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LETMD1 LETM1 domain containing 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LHFP lipoma HMGIC fusion partner
LIMCH1 LIM and calponin homology domains 1
LOC100272216 uncharacterized LOC100272216
LOC399491
LOX lysyl oxidase
LRRC15 leucine rich repeat containing 15
LRRC17 leucine rich repeat containing 17
LTBP3 latent transforming growth factor beta binding protein 3
LY96 lymphocyte antigen 96
LYPD1 LY6/PLAUR domain containing 1
LYZ lysozyme
MAGED1 melanoma antigen family D1
MAGED2 melanoma antigen family D2
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP1B microtubule-associated protein 1B
MEIS1 Meis homeobox 1
MFAP5 microfibrillar associated protein 5
MMP1 matrix metallopeptidase 1
MSLN mesothelin
MTSS1 metastasis suppressor 1
MUC16 mucin 16, cell surface associated
MVP major vault protein
MXI1 MAX interactor 1, dimerization protein
MXRA5 matrix-remodelling associated 5
MYRF myelin regulatory factor
MZF1 myeloid zinc finger 1
N4BP2L2 NEDD4 binding protein 2-like 2
NARFL nuclear prelamin A recognition factor-like
NBR1 neighbor of BRCA1 gene 1
NCALD neurocalcin delta
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NELL2 NEL-like 2 (chicken)
NONO non-POU domain containing, octamer-binding
NPDC1 neural proliferation, differentiation and control, 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NR4A2 nuclear receptor subfamily 4, group A, member 2
NSG1 neuron specific gene family member 1
NTM neurotrimin
NUPR1 nuclear protein, transcriptional regulator, 1
OBSL1 obscurin-like 1
OFD1 oral-facial-digital syndrome 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OLFM1 olfactomedin 1
OLFM4 olfactomedin 4
OPHN1 oligophrenin 1
ORAI3 ORAI calcium release-activated calcium modulator 3
ORM1 orosomucoid 1
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PEG3 paternally expressed 3
PFDN5 prefoldin subunit 5
PHIP pleckstrin homology domain interacting protein
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1
PLCB4 phospholipase C, beta 4
PLXNC1 plexin C1
PNKP polynucleotide kinase 3'-phosphatase
PNRC1 proline-rich nuclear receptor coactivator 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRAF2 PRA1 domain family, member 2
PRAME preferentially expressed antigen in melanoma
PRUNE2 prune homolog 2 (Drosophila)
PTCH1 patched 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRG protein tyrosine phosphatase, receptor type, G
RALGDS ral guanine nucleotide dissociation stimulator
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL39L ribosomal protein L39-like
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD5 stearoyl-CoA desaturase 5
SEC31A SEC31 homolog A (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERINC3 serine incorporator 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SFRP1 secreted frizzled-related protein 1
SH3YL1 SH3 and SYLF domain containing 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC35E2B solute carrier family 35, member E2B
SLC38A10 solute carrier family 38, member 10
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SOD2 superoxide dismutase 2, mitochondrial
SPATA20 spermatogenesis associated 20
SPINK1 serine peptidase inhibitor, Kazal type 1
SRRM2 serine/arginine repetitive matrix 2
SST somatostatin
ST18 suppression of tumorigenicity 18, zinc finger
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STK38L serine/threonine kinase 38 like
STS steroid sulfatase (microsomal), isozyme S
STX1A syntaxin 1A (brain)
SULF1 sulfatase 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SYBU syntabulin (syntaxin-interacting)
TBX3 T-box 3
TCTN1 tectonic family member 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
THBS2 thrombospondin 2
THBS3 thrombospondin 3
TMC5 transmembrane channel-like 5
TMED3 transmembrane emp24 protein transport domain containing 3
TMEM110 transmembrane protein 110
TMEM45A transmembrane protein 45A
TMOD1 tropomodulin 1
TPGS2 tubulin polyglutamylase complex subunit 2
TPP1 tripeptidyl peptidase I
TRIM2 tripartite motif containing 2
TRIM22 tripartite motif containing 22
TRPS1 trichorhinophalangeal syndrome I
TSC2 tuberous sclerosis 2
TSC22D1 TSC22 domain family, member 1
TSPAN7 tetraspanin 7
TST thiosulfate sulfurtransferase (rhodanese)
TSTA3 tissue specific transplantation antigen P35B
TXNIP thioredoxin interacting protein
VCAN versican
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WDR13 WD repeat domain 13
WDR45 WD repeat domain 45
WDTC1 WD and tetratricopeptide repeats 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
XYLT1 xylosyltransferase I
YPEL5 yippee-like 5 (Drosophila)
ZDHHC11 zinc finger, DHHC-type containing 11
ZFPM2 zinc finger protein, FOG family member 2
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADI1 acireductone dioxygenase 1
ADIRF adipogenesis regulatory factor
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AK4 adenylate kinase 4
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ANPEP alanyl (membrane) aminopeptidase
ANXA3 annexin A3
APOC1 apolipoprotein C-I
AQP3 aquaporin 3 (Gill blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARPC5L actin related protein 2/3 complex, subunit 5-like
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATAD2 ATPase family, AAA domain containing 2
AURKA aurora kinase A
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BRCA1 breast cancer 1, early onset
BST2 bone marrow stromal cell antigen 2
C7 complement component 7
CA12 carbonic anhydrase XII
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CCDC86 coiled-coil domain containing 86
CCNA2 cyclin A2
CCND3 cyclin D3
CCNE2 cyclin E2
CD24 CD24 molecule
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CDKN3 cyclin-dependent kinase inhibitor 3
CKS2 CDC28 protein kinase regulatory subunit 2
CLU clusterin
CMC2 C-x(9)-C motif containing 2
COL4A2 collagen, type IV, alpha 2
CPVL carboxypeptidase, vitellogenic-like
CRYAB crystallin, alpha B
CSTA cystatin A (stefin A)
CXCL6 chemokine (C-X-C motif) ligand 6
CYB5A cytochrome b5 type A (microsomal)
CYCS cytochrome c, somatic
DBF4 DBF4 zinc finger
DEFB1 defensin, beta 1
DNASE1L3 deoxyribonuclease I-like 3
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DYNLT1 dynein, light chain, Tctex-type 1
EBNA1BP2 EBNA1 binding protein 2
EBP emopamil binding protein (sterol isomerase)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF4A3 eukaryotic translation initiation factor 4A3
EIF4E eukaryotic translation initiation factor 4E
EMX2 empty spiracles homeobox 2
ENO1 enolase 1, (alpha)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHA3 EPH receptor A3
ETF1 eukaryotic translation termination factor 1
EZR ezrin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM162A family with sequence similarity 162, member A
FAM69A family with sequence similarity 69, member A
FEN1 flap structure-specific endonuclease 1
FKBP11 FK506 binding protein 11, 19 kDa
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GPX3 glutathione peroxidase 3
H2AFX H2A histone family, member X
H2AFZ H2A histone family, member Z
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HOXA5 homeobox A5
HOXC10 homeobox C10
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA14 heat shock 70kDa protein 14
HSPA8 heat shock 70kDa protein 8
HSPB8 heat shock 22kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IARS isoleucyl-tRNA synthetase
IGFBP6 insulin-like growth factor binding protein 6
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCTD12 potassium channel tetramerization domain containing 12
KIAA0101 KIAA0101
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT5 keratin 5, type II
KRT7 keratin 7, type II
LBR lamin B receptor
LMNB1 lamin B1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MARCKS myristoylated alanine-rich protein kinase C substrate
MCM10 minichromosome maintenance complex component 10
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MCUR1 mitochondrial calcium uniporter regulator 1
MELK maternal embryonic leucine zipper kinase
MICALL1 MICAL-like 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MME membrane metallo-endopeptidase
MSMB microseminoprotein, beta-
MT1G metallothionein 1G
MT1M metallothionein 1M
MT1X metallothionein 1X
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYBPC1 myosin binding protein C, slow type
MYLK myosin light chain kinase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NEFL neurofilament, light polypeptide
NKX3-1 NK3 homeobox 1
NLRP2 NLR family, pyrin domain containing 2
NT5DC2 5'-nucleotidase domain containing 2
NUSAP1 nucleolar and spindle associated protein 1
NXT1 nuclear transport factor 2-like export factor 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PARP2 poly (ADP-ribose) polymerase 2
PAX5 paired box 5
PBK PDZ binding kinase
PCNA proliferating cell nuclear antigen
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PDZK1 PDZ domain containing 1
PEA15 phosphoprotein enriched in astrocytes 15
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKP phosphofructokinase, platelet
PGAM1 phosphoglycerate mutase 1 (brain)
PGK1 phosphoglycerate kinase 1
PIP prolactin-induced protein
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PPIF peptidylprolyl isomerase F
PRKCA protein kinase C, alpha
PRR15L proline rich 15-like
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB4A RAB4A, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RFC4 replication factor C (activator 1) 4, 37kDa
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
RPA3 replication protein A3, 14kDa
RPIA ribose 5-phosphate isomerase A
RPS11 ribosomal protein S11
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RRM2 ribonucleotide reductase M2
RUVBL1 RuvB-like AAA ATPase 1
S100A10 S100 calcium binding protein A10
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SACS sacsin molecular chaperone
SCGB2A2 secretoglobin, family 2A, member 2
SDC2 syndecan 2
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEPHS1 selenophosphate synthetase 1
SGK1 serum/glucocorticoid regulated kinase 1
SHCBP1 SHC SH2-domain binding protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35F2 solute carrier family 35, member F2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPG small nuclear ribonucleoprotein polypeptide G
SNX10 sorting nexin 10
SPC25 SPC25, NDC80 kinetochore complex component
SRSF3 serine/arginine-rich splicing factor 3
SRSF7 serine/arginine-rich splicing factor 7
STK17A serine/threonine kinase 17a
STMN1 stathmin 1
SUMO3 small ubiquitin-like modifier 3
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TACC1 transforming, acidic coiled-coil containing protein 1
TF transferrin
TFAM transcription factor A, mitochondrial
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFF3 trefoil factor 3 (intestinal)
TFRC transferrin receptor
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TIPIN TIMELESS interacting protein
TJP2 tight junction protein 2
TM4SF1 transmembrane 4 L six family member 1
TMEM176B transmembrane protein 176B
TMEM70 transmembrane protein 70
TMPO thymopoietin
TPM4 tropomyosin 4
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TRIP13 thyroid hormone receptor interactor 13
TUBG1 tubulin, gamma 1
TWF1 twinfilin actin binding protein 1
TYMS thymidylate synthetase
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VBP1 von Hippel-Lindau binding protein 1
VCAM1 vascular cell adhesion molecule 1
VDAC1 voltage-dependent anion channel 1
VGLL4 vestigial-like family member 4
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
VRK1 vaccinia related kinase 1
WSB2 WD repeat and SOCS box containing 2
WT1 Wilms tumor 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZMYM2 zinc finger, MYM-type 2
ZNF22 zinc finger protein 22
Funding