| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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148 genes differentially expressed following the BRD-K02708799_GSK-1059615_HS578T_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ABHD4 | abhydrolase domain containing 4 |
| ACPP | acid phosphatase, prostate |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| APOD | apolipoprotein D |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CNPY3 | canopy FGF signaling regulator 3 |
| COL10A1 | collagen, type X, alpha 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYTIP | cytohesin 1 interacting protein |
| DCN | decorin |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DPP4 | dipeptidyl-peptidase 4 |
| DSP | desmoplakin |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPHA3 | EPH receptor A3 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FGFR1 | fibroblast growth factor receptor 1 |
| FNBP1 | formin binding protein 1 |
| FZD7 | frizzled class receptor 7 |
| GAS1 | growth arrest-specific 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GSN | gelsolin |
| IDS | iduronate 2-sulfatase |
| IER3 | immediate early response 3 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| ITGAV | integrin, alpha V |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL21 | kelch-like family member 21 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LUM | lumican |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAGED1 | melanoma antigen family D1 |
| MAP1B | microtubule-associated protein 1B |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MDK | midkine (neurite growth-promoting factor 2) |
| MSMB | microseminoprotein, beta- |
| NEFH | neurofilament, heavy polypeptide |
| NOTCH2NL | notch 2 N-terminal like |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PEG10 | paternally expressed 10 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
| PSAP | prosaposin |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTN | pleiotrophin |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RGS2 | regulator of G-protein signaling 2 |
| RORA | RAR-related orphan receptor A |
| RPS11 | ribosomal protein S11 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SESN1 | sestrin 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPP1 | secreted phosphoprotein 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STX1A | syntaxin 1A (brain) |
| SYNGR3 | synaptogyrin 3 |
| SYNM | synemin, intermediate filament protein |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TRIM13 | tripartite motif containing 13 |
| TXNIP | thioredoxin interacting protein |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| ZNF586 | zinc finger protein 586 |
| Symbol | Name |
|---|---|
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| AMD1 | adenosylmethionine decarboxylase 1 |
| AREG | amphiregulin |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| C1QA | complement component 1, q subcomponent, A chain |
| CCND1 | cyclin D1 |
| CDC25A | cell division cycle 25A |
| CLDN7 | claudin 7 |
| CLTB | clathrin, light chain B |
| CTSZ | cathepsin Z |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CYCS | cytochrome c, somatic |
| DDIT4 | DNA-damage-inducible transcript 4 |
| EGFR | epidermal growth factor receptor |
| EIF5A | eukaryotic translation initiation factor 5A |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GSTT1 | glutathione S-transferase theta 1 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA2 | heat shock 70kDa protein 2 |
| IL1R2 | interleukin 1 receptor, type II |
| IL32 | interleukin 32 |
| ITGB1BP1 | integrin beta 1 binding protein 1 |
| LAMA3 | laminin, alpha 3 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LRRC59 | leucine rich repeat containing 59 |
| LYZ | lysozyme |
| MAGEA3 | melanoma antigen family A3 |
| MAT2A | methionine adenosyltransferase II, alpha |
| MREG | melanoregulin |
| NCAM1 | neural cell adhesion molecule 1 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NPTX2 | neuronal pentraxin II |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PI3 | peptidase inhibitor 3, skin-derived |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKCH | protein kinase C, eta |
| PSCA | prostate stem cell antigen |
| RASIP1 | Ras interacting protein 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SACM1L | SAC1 suppressor of actin mutations 1-like (yeast) |
| SCG5 | secretogranin V |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
| SIRT3 | sirtuin 3 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMAGP | small cell adhesion glycoprotein |
| SRI | sorcin |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TMEM97 | transmembrane protein 97 |
| TMSB15A | thymosin beta 15a |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TSPAN8 | tetraspanin 8 |
| TTC39A | tetratricopeptide repeat domain 39A |
| VAT1 | vesicle amine transport 1 |
| VDAC1 | voltage-dependent anion channel 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
