| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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242 genes differentially expressed following the BRD-K02708799_GSK-1059615_MCF10A_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADD3 | adducin 3 (gamma) |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANGPTL2 | angiopoietin-like 2 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ANKRD10 | ankyrin repeat domain 10 |
| AUTS2 | autism susceptibility candidate 2 |
| BLNK | B-cell linker |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BST2 | bone marrow stromal cell antigen 2 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C3 | complement component 3 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CBR3 | carbonyl reductase 3 |
| CCNG2 | cyclin G2 |
| CDK14 | cyclin-dependent kinase 14 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CFH | complement factor H |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLEC2B | C-type lectin domain family 2, member B |
| COL11A1 | collagen, type XI, alpha 1 |
| CPD | carboxypeptidase D |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DUSP1 | dual specificity phosphatase 1 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFHD1 | EF-hand domain family, member D1 |
| EGFR | epidermal growth factor receptor |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM13A | family with sequence similarity 13, member A |
| FHL1 | four and a half LIM domains 1 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATA3 | GATA binding protein 3 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLUL | glutamate-ammonia ligase |
| GPX4 | glutathione peroxidase 4 |
| GRN | granulin |
| H2BFS | H2B histone family, member S (pseudogene) |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| HP | haptoglobin |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IFI44L | interferon-induced protein 44-like |
| IRS2 | insulin receptor substrate 2 |
| JUP | junction plakoglobin |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KIAA0907 | KIAA0907 |
| KIF14 | kinesin family member 14 |
| KLF9 | Kruppel-like factor 9 |
| LOX | lysyl oxidase |
| LPL | lipoprotein lipase |
| MAGED1 | melanoma antigen family D1 |
| MARCH2 | membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase |
| MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
| MDFIC | MyoD family inhibitor domain containing |
| METTL7A | methyltransferase like 7A |
| MFAP5 | microfibrillar associated protein 5 |
| MGP | matrix Gla protein |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PEG10 | paternally expressed 10 |
| PLBD1 | phospholipase B domain containing 1 |
| PLXNB2 | plexin B2 |
| POSTN | periostin, osteoblast specific factor |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPL | periplakin |
| PTK2 | protein tyrosine kinase 2 |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RGS1 | regulator of G-protein signaling 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RSRP1 | arginine/serine-rich protein 1 |
| SCPEP1 | serine carboxypeptidase 1 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SEPT10 | septin 10 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SESN1 | sestrin 1 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC35E2B | solute carrier family 35, member E2B |
| SLC35F2 | solute carrier family 35, member F2 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TCTA | T-cell leukemia translocation altered |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TJP2 | tight junction protein 2 |
| TMEM140 | transmembrane protein 140 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSC22D3 | TSC22 domain family, member 3 |
| TXNIP | thioredoxin interacting protein |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| WDR61 | WD repeat domain 61 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZBTB16 | zinc finger and BTB domain containing 16 |
| ZIC1 | Zic family member 1 |
| Symbol | Name |
|---|---|
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADI1 | acireductone dioxygenase 1 |
| ADRB2 | adrenoceptor beta 2, surface |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| AQP3 | aquaporin 3 (Gill blood group) |
| BAG2 | BCL2-associated athanogene 2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CALML3 | calmodulin-like 3 |
| CCND1 | cyclin D1 |
| CCND2 | cyclin D2 |
| CDC25A | cell division cycle 25A |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
| COG2 | component of oligomeric golgi complex 2 |
| CTSC | cathepsin C |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 |
| DUSP14 | dual specificity phosphatase 14 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EFHD2 | EF-hand domain family, member D2 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EHD1 | EH-domain containing 1 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa |
| EIF5A | eukaryotic translation initiation factor 5A |
| EPHA2 | EPH receptor A2 |
| EREG | epiregulin |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM129A | family with sequence similarity 129, member A |
| FAM98A | family with sequence similarity 98, member A |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FHL2 | four and a half LIM domains 2 |
| FOSL1 | FOS-like antigen 1 |
| FST | follistatin |
| GDF15 | growth differentiation factor 15 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GSTA1 | glutathione S-transferase alpha 1 |
| GTPBP4 | GTP binding protein 4 |
| HBEGF | heparin-binding EGF-like growth factor |
| HMGA2 | high mobility group AT-hook 2 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXA10 | homeobox A10 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPA8 | heat shock 70kDa protein 8 |
| IER2 | immediate early response 2 |
| IER3 | immediate early response 3 |
| IL1B | interleukin 1, beta |
| KLF10 | Kruppel-like factor 10 |
| KLK10 | kallikrein-related peptidase 10 |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| LBR | lamin B receptor |
| LCN2 | lipocalin 2 |
| LPXN | leupaxin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MAT2A | methionine adenosyltransferase II, alpha |
| MMP12 | matrix metallopeptidase 12 |
| MSMB | microseminoprotein, beta- |
| MSMO1 | methylsterol monooxygenase 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NKX3-1 | NK3 homeobox 1 |
| NOP16 | NOP16 nucleolar protein |
| NOP56 | NOP56 ribonucleoprotein |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OAT | ornithine aminotransferase |
| ODC1 | ornithine decarboxylase 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PI3 | peptidase inhibitor 3, skin-derived |
| PITX1 | paired-like homeodomain 1 |
| PLAU | plasminogen activator, urokinase |
| PLK2 | polo-like kinase 2 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| PNP | purine nucleoside phosphorylase |
| PODXL | podocalyxin-like |
| POPDC3 | popeye domain containing 3 |
| PPIF | peptidylprolyl isomerase F |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRSS3 | protease, serine, 3 |
| PTHLH | parathyroid hormone-like hormone |
| REG1A | regenerating islet-derived 1 alpha |
| REG3A | regenerating islet-derived 3 alpha |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A2 | S100 calcium binding protein A2 |
| S100A9 | S100 calcium binding protein A9 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SDC4 | syndecan 4 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERTAD2 | SERTA domain containing 2 |
| SFN | stratifin |
| SH2B3 | SH2B adaptor protein 3 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRR1A | small proline-rich protein 1A |
| SPRR2B | small proline-rich protein 2B |
| SPRR3 | small proline-rich protein 3 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TBP | TATA box binding protein |
| TFF3 | trefoil factor 3 (intestinal) |
| TLR4 | toll-like receptor 4 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIB2 | tribbles pseudokinase 2 |
| TSPYL5 | TSPY-like 5 |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB6 | tubulin, beta 6 class V |
| WFDC2 | WAP four-disulfide core domain 2 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
