BRD-K02822062_CT-200783_HEC108_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-K02822062_CT-200783_HEC108_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANKRD10 ankyrin repeat domain 10
ATF6 activating transcription factor 6
ATP11B ATPase, class VI, type 11B
ATXN7 ataxin 7
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CD200 CD200 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC4 chloride intracellular channel 4
CNOT4 CCR4-NOT transcription complex, subunit 4
CORO1A coronin, actin binding protein, 1A
CPE carboxypeptidase E
CREB1 cAMP responsive element binding protein 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EMX2 empty spiracles homeobox 2
FAM129A family with sequence similarity 129, member A
GEM GTP binding protein overexpressed in skeletal muscle
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
JCHAIN joining chain of multimeric IgA and IgM
JMJD6 jumonji domain containing 6
KPNB1 karyopherin (importin) beta 1
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MED13 mediator complex subunit 13
MTF2 metal response element binding transcription factor 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRCAM neuronal cell adhesion molecule
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PLTP phospholipid transfer protein
PRKCI protein kinase C, iota
PRKX protein kinase, X-linked
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RGS1 regulator of G-protein signaling 1
RYBP RING1 and YY1 binding protein
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERTAD2 SERTA domain containing 2
SH3GLB1 SH3-domain GRB2-like endophilin B1
SMAD1 SMAD family member 1
SNX7 sorting nexin 7
SRSF11 serine/arginine-rich splicing factor 11
TLE4 transducin-like enhancer of split 4
TTC3 tetratricopeptide repeat domain 3
TXNL4B thioredoxin-like 4B
TXNRD1 thioredoxin reductase 1
TYROBP TYRO protein tyrosine kinase binding protein
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
XIST X inactive specific transcript (non-protein coding)
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1

decreased expression

Symbol Name
AMDHD2 amidohydrolase domain containing 2
ASPH aspartate beta-hydroxylase
CAST calpastatin
CDC25B cell division cycle 25B
CHN2 chimerin 2
CHPT1 choline phosphotransferase 1
CIB1 calcium and integrin binding 1 (calmyrin)
CLDN1 claudin 1
CNPY2 canopy FGF signaling regulator 2
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DSP desmoplakin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EML3 echinoderm microtubule associated protein like 3
EMP3 epithelial membrane protein 3
EXOSC4 exosome component 4
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GRWD1 glutamate-rich WD repeat containing 1
IFI6 interferon, alpha-inducible protein 6
IGFBP3 insulin-like growth factor binding protein 3
ISG15 ISG15 ubiquitin-like modifier
MICALL1 MICAL-like 1
MRPL12 mitochondrial ribosomal protein L12
MX2 MX dynamin-like GTPase 2
NFIB nuclear factor I/B
PALLD palladin, cytoskeletal associated protein
PARP12 poly (ADP-ribose) polymerase family, member 12
PLAU plasminogen activator, urokinase
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
REG1A regenerating islet-derived 1 alpha
SFRP1 secreted frizzled-related protein 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
THBS1 thrombospondin 1
TM7SF2 transmembrane 7 superfamily member 2
TSPYL5 TSPY-like 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Funding