BRD-K03063480_PF-477736_HS578T_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K03063480_PF-477736_HS578T_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADA adenosine deaminase
ADIRF adipogenesis regulatory factor
AQP3 aquaporin 3 (Gill blood group)
BHLHE41 basic helix-loop-helix family, member e41
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CST3 cystatin C
CSTA cystatin A (stefin A)
CYBRD1 cytochrome b reductase 1
DCN decorin
DEFB1 defensin, beta 1
DSP desmoplakin
F13A1 coagulation factor XIII, A1 polypeptide
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM46A family with sequence similarity 46, member A
G0S2 G0/G1 switch 2
GPX3 glutathione peroxidase 3
GRN granulin
GSN gelsolin
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFI27 interferon, alpha-inducible protein 27
ISG15 ISG15 ubiquitin-like modifier
ITGB4 integrin, beta 4
JUP junction plakoglobin
KIAA1033 KIAA1033
KRT6A keratin 6A, type II
LCN2 lipocalin 2
NDRG1 N-myc downstream regulated 1
NUPR1 nuclear protein, transcriptional regulator, 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PILRB paired immunoglobin-like type 2 receptor beta
RRAGD Ras-related GTP binding D
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFN stratifin
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
TPBG trophoblast glycoprotein
TRIM29 tripartite motif containing 29
TYROBP TYRO protein tyrosine kinase binding protein
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
XIST X inactive specific transcript (non-protein coding)
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
C2CD5 C2 calcium-dependent domain containing 5
CCNA2 cyclin A2
CDK1 cyclin-dependent kinase 1
CHEK2 checkpoint kinase 2
CXCL9 chemokine (C-X-C motif) ligand 9
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FABP7 fatty acid binding protein 7, brain
FGG fibrinogen gamma chain
FOSL1 FOS-like antigen 1
FOXM1 forkhead box M1
KCNK3 potassium channel, two pore domain subfamily K, member 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MELK maternal embryonic leucine zipper kinase
MET MET proto-oncogene, receptor tyrosine kinase
MID1 midline 1
MYO10 myosin X
NET1 neuroepithelial cell transforming 1
RFC2 replication factor C (activator 1) 2, 40kDa
RRM2 ribonucleotide reductase M2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
TOP2A topoisomerase (DNA) II alpha 170kDa
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
ZDHHC6 zinc finger, DHHC-type containing 6
ZWINT ZW10 interacting kinetochore protein
Funding