Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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128 genes differentially expressed following the BRD-K03063480_PF-477736_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABHD6 | abhydrolase domain containing 6 |
ALCAM | activated leukocyte cell adhesion molecule |
AREG | amphiregulin |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATF3 | activating transcription factor 3 |
AXIN1 | axin 1 |
BAMBI | BMP and activin membrane-bound inhibitor |
CARS | cysteinyl-tRNA synthetase |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CXORF40A | chromosome X open reading frame 40A |
CXORF40B | chromosome X open reading frame 40B |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
FADS1 | fatty acid desaturase 1 |
FADS2 | fatty acid desaturase 2 |
FGL2 | fibrinogen-like 2 |
GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
GAS1 | growth arrest-specific 1 |
GLUL | glutamate-ammonia ligase |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HIST1H2BD | histone cluster 1, H2bd |
HIST1H2BK | histone cluster 1, H2bk |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HSPA2 | heat shock 70kDa protein 2 |
IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
KIF14 | kinesin family member 14 |
KYNU | kynureninase |
LMO2 | LIM domain only 2 (rhombotin-like 1) |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
METRN | meteorin, glial cell differentiation regulator |
MIR22HG | MIR22 host gene |
MSL1 | male-specific lethal 1 homolog (Drosophila) |
MT1X | metallothionein 1X |
NKX2-2 | NK2 homeobox 2 |
NPTX2 | neuronal pentraxin II |
NPY1R | neuropeptide Y receptor Y1 |
NR0B1 | nuclear receptor subfamily 0, group B, member 1 |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
NTS | neurotensin |
NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 |
OLFM1 | olfactomedin 1 |
PDLIM3 | PDZ and LIM domain 3 |
PTN | pleiotrophin |
RABAC1 | Rab acceptor 1 (prenylated) |
RAP2A | RAP2A, member of RAS oncogene family |
RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
RBP1 | retinol binding protein 1, cellular |
RND3 | Rho family GTPase 3 |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SFRP4 | secreted frizzled-related protein 4 |
SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
SGK1 | serum/glucocorticoid regulated kinase 1 |
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
TNNT1 | troponin T type 1 (skeletal, slow) |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
UGDH | UDP-glucose 6-dehydrogenase |
USO1 | USO1 vesicle transport factor |
XIST | X inactive specific transcript (non-protein coding) |
Symbol | Name |
---|---|
AGTR1 | angiotensin II receptor, type 1 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
ANXA4 | annexin A4 |
ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
BTBD3 | BTB (POZ) domain containing 3 |
C10ORF10 | chromosome 10 open reading frame 10 |
CBR3 | carbonyl reductase 3 |
CD24 | CD24 molecule |
CD93 | CD93 molecule |
CHEK1 | checkpoint kinase 1 |
COL1A1 | collagen, type I, alpha 1 |
COL1A2 | collagen, type I, alpha 2 |
COL6A1 | collagen, type VI, alpha 1 |
COL6A3 | collagen, type VI, alpha 3 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DMBT1 | deleted in malignant brain tumors 1 |
DOK5 | docking protein 5 |
DPP4 | dipeptidyl-peptidase 4 |
DSP | desmoplakin |
EAPP | E2F-associated phosphoprotein |
EFNA1 | ephrin-A1 |
FGFR3 | fibroblast growth factor receptor 3 |
FN1 | fibronectin 1 |
IGFBP7 | insulin-like growth factor binding protein 7 |
JAG1 | jagged 1 |
KAZN | kazrin, periplakin interacting protein |
KCTD12 | potassium channel tetramerization domain containing 12 |
KDM5D | lysine (K)-specific demethylase 5D |
KIF20A | kinesin family member 20A |
KRT7 | keratin 7, type II |
LAMA4 | laminin, alpha 4 |
LOC100505650 | uncharacterized LOC100505650 |
LPL | lipoprotein lipase |
MAOA | monoamine oxidase A |
MCAM | melanoma cell adhesion molecule |
MCM2 | minichromosome maintenance complex component 2 |
MCM5 | minichromosome maintenance complex component 5 |
MCM6 | minichromosome maintenance complex component 6 |
MGP | matrix Gla protein |
MSN | moesin |
NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
NREP | neuronal regeneration related protein |
OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 |
PCNA | proliferating cell nuclear antigen |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
POSTN | periostin, osteoblast specific factor |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
RAB25 | RAB25, member RAS oncogene family |
RBPMS | RNA binding protein with multiple splicing |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SDC4 | syndecan 4 |
SFTPA2 | surfactant protein A2 |
SFTPB | surfactant protein B |
SFTPC | surfactant protein C |
SOX4 | SRY (sex determining region Y)-box 4 |
SST | somatostatin |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TM4SF1 | transmembrane 4 L six family member 1 |
TM4SF4 | transmembrane 4 L six family member 4 |
TMX4 | thioredoxin-related transmembrane protein 4 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TYMS | thymidylate synthetase |
ZNF395 | zinc finger protein 395 |