| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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75 genes differentially expressed following the BRD-K03063480_PF-477736_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ATF3 | activating transcription factor 3 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CCND2 | cyclin D2 |
| CCNG2 | cyclin G2 |
| CD9 | CD9 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DDIT4 | DNA-damage-inducible transcript 4 |
| ECM1 | extracellular matrix protein 1 |
| FN1 | fibronectin 1 |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GAS6 | growth arrest-specific 6 |
| GPX1 | glutathione peroxidase 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| INPP1 | inositol polyphosphate-1-phosphatase |
| LIMCH1 | LIM and calponin homology domains 1 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MIR22HG | MIR22 host gene |
| PEG10 | paternally expressed 10 |
| PERP | PERP, TP53 apoptosis effector |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| RAP1GAP | RAP1 GTPase activating protein |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RND3 | Rho family GTPase 3 |
| S100A14 | S100 calcium binding protein A14 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCPEP1 | serine carboxypeptidase 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TRIM22 | tripartite motif containing 22 |
| VCAN | versican |
| VIM | vimentin |
| Symbol | Name |
|---|---|
| ALOX5 | arachidonate 5-lipoxygenase |
| ATAD2 | ATPase family, AAA domain containing 2 |
| CA2 | carbonic anhydrase II |
| CCNA2 | cyclin A2 |
| CCNE2 | cyclin E2 |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDCA4 | cell division cycle associated 4 |
| CDK1 | cyclin-dependent kinase 1 |
| CFH | complement factor H |
| CHEK2 | checkpoint kinase 2 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EMP2 | epithelial membrane protein 2 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GMNN | geminin, DNA replication inhibitor |
| IFITM1 | interferon induced transmembrane protein 1 |
| ITM2A | integral membrane protein 2A |
| LMNB1 | lamin B1 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MSH2 | mutS homolog 2 |
| MSH6 | mutS homolog 6 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PSIP1 | PC4 and SFRS1 interacting protein 1 |
| RBP1 | retinol binding protein 1, cellular |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| TMPO | thymopoietin |
| ZEB2 | zinc finger E-box binding homeobox 2 |
