BRD-K03063480_PF-477736_MDAMB231_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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34 genes differentially expressed following the BRD-K03063480_PF-477736_MDAMB231_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLDN10 claudin 10
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
DUSP6 dual specificity phosphatase 6
GABARAPL1 GABA(A) receptor-associated protein like 1
GARS glycyl-tRNA synthetase
ICAM1 intercellular adhesion molecule 1
MXI1 MAX interactor 1, dimerization protein
NTS neurotensin
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEG3 paternally expressed 3
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A6 solute carrier family 16, member 6
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
VNN1 vanin 1
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
CENPU centromere protein U
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EFNB2 ephrin-B2
FABP7 fatty acid binding protein 7, brain
FXYD5 FXYD domain containing ion transport regulator 5
GATA3 GATA binding protein 3
IFI44 interferon-induced protein 44
LTF lactotransferrin
REEP1 receptor accessory protein 1
RRM2 ribonucleotide reductase M2
TIMP3 TIMP metallopeptidase inhibitor 3