BRD-K03109492_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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27 genes differentially expressed following the BRD-K03109492_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BRD4 bromodomain containing 4
CCL13 chemokine (C-C motif) ligand 13
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
HIST1H1C histone cluster 1, H1c
KLF4 Kruppel-like factor 4 (gut)
LDLR low density lipoprotein receptor
LMNA lamin A/C
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K5 mitogen-activated protein kinase kinase 5
NEU1 sialidase 1 (lysosomal sialidase)
PHLDA2 pleckstrin homology-like domain, family A, member 2
RNH1 ribonuclease/angiogenin inhibitor 1
SIDT2 SID1 transmembrane family, member 2
STAB1 stabilin 1
TPPP3 tubulin polymerization-promoting protein family member 3

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
BEX1 brain expressed, X-linked 1
C6ORF62 chromosome 6 open reading frame 62
CLIC4 chloride intracellular channel 4
FHL1 four and a half LIM domains 1
FPGS folylpolyglutamate synthase
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GSTM3 glutathione S-transferase mu 3 (brain)
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)