| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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97 genes differentially expressed following the BRD-K03449891_foretinib_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| ADIRF | adipogenesis regulatory factor |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ANGPTL2 | angiopoietin-like 2 |
| ANXA10 | annexin A10 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C4BPA | complement component 4 binding protein, alpha |
| CBR3 | carbonyl reductase 3 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CTSK | cathepsin K |
| CXORF57 | chromosome X open reading frame 57 |
| DUSP6 | dual specificity phosphatase 6 |
| EMP2 | epithelial membrane protein 2 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FST | follistatin |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPX4 | glutathione peroxidase 4 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| GRN | granulin |
| HMOX1 | heme oxygenase 1 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IRS1 | insulin receptor substrate 1 |
| LDLR | low density lipoprotein receptor |
| LIMCH1 | LIM and calponin homology domains 1 |
| MATN2 | matrilin 2 |
| MEIS2 | Meis homeobox 2 |
| METTL7A | methyltransferase like 7A |
| MID1 | midline 1 |
| MPDZ | multiple PDZ domain protein |
| NAV2 | neuron navigator 2 |
| NKG7 | natural killer cell granule protein 7 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PIR | pirin (iron-binding nuclear protein) |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRKCQ | protein kinase C, theta |
| PTK2B | protein tyrosine kinase 2 beta |
| PTPRK | protein tyrosine phosphatase, receptor type, K |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC38A1 | solute carrier family 38, member 1 |
| SNN | stannin |
| SNX11 | sorting nexin 11 |
| SQSTM1 | sequestosome 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| USP6NL | USP6 N-terminal like |
| Symbol | Name |
|---|---|
| AK4 | adenylate kinase 4 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| AMD1 | adenosylmethionine decarboxylase 1 |
| BLVRA | biliverdin reductase A |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| CLIC4 | chloride intracellular channel 4 |
| COL9A3 | collagen, type IX, alpha 3 |
| CPD | carboxypeptidase D |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| FAM60A | family with sequence similarity 60, member A |
| FAS | Fas cell surface death receptor |
| GLIPR1 | GLI pathogenesis-related 1 |
| GOLM1 | golgi membrane protein 1 |
| GOLT1B | golgi transport 1B |
| IER3 | immediate early response 3 |
| KRT10 | keratin 10, type I |
| KRT14 | keratin 14, type I |
| LCN2 | lipocalin 2 |
| LTF | lactotransferrin |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MAP7 | microtubule-associated protein 7 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCNA | proliferating cell nuclear antigen |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAT | plasminogen activator, tissue |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PRPF4 | pre-mRNA processing factor 4 |
| SEPT11 | septin 11 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC35F2 | solute carrier family 35, member F2 |
| TBC1D4 | TBC1 domain family, member 4 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TMED9 | transmembrane emp24 protein transport domain containing 9 |
| TUBB2A | tubulin, beta 2A class IIa |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| UGDH | UDP-glucose 6-dehydrogenase |
| VCAN | versican |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
