| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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82 genes differentially expressed following the BRD-K03449891_foretinib_HEPG2_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ANXA11 | annexin A11 |
| BBX | bobby sox homolog (Drosophila) |
| CARS | cysteinyl-tRNA synthetase |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD47 | CD47 molecule |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| DAPK1 | death-associated protein kinase 1 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 |
| EGFR | epidermal growth factor receptor |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| GPX2 | glutathione peroxidase 2 |
| HIST1H2AC | histone cluster 1, H2ac |
| IGF1R | insulin-like growth factor 1 receptor |
| IGKC | immunoglobulin kappa constant |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| KIAA0753 | KIAA0753 |
| KLF6 | Kruppel-like factor 6 |
| KRT23 | keratin 23, type I |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LCN2 | lipocalin 2 |
| LEPROT | leptin receptor overlapping transcript |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LY96 | lymphocyte antigen 96 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MME | membrane metallo-endopeptidase |
| MMP7 | matrix metallopeptidase 7 |
| MVP | major vault protein |
| NAV2 | neuron navigator 2 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PSAT1 | phosphoserine aminotransferase 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| STAB1 | stabilin 1 |
| TCF4 | transcription factor 4 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| ZIC1 | Zic family member 1 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| CA2 | carbonic anhydrase II |
| CCNE2 | cyclin E2 |
| CCNF | cyclin F |
| CD200 | CD200 molecule |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDC6 | cell division cycle 6 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CSTA | cystatin A (stefin A) |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EPHA3 | EPH receptor A3 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| FEN1 | flap structure-specific endonuclease 1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GNAS | GNAS complex locus |
| H2AFX | H2A histone family, member X |
| HIST1H2BG | histone cluster 1, H2bg |
| KRT19 | keratin 19, type I |
| MAGEB2 | melanoma antigen family B2 |
| MAOB | monoamine oxidase B |
| MCM2 | minichromosome maintenance complex component 2 |
| MSLN | mesothelin |
| ODC1 | ornithine decarboxylase 1 |
| PBK | PDZ binding kinase |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRC1 | protein regulator of cytokinesis 1 |
| RACGAP1 | Rac GTPase activating protein 1 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RRM2 | ribonucleotide reductase M2 |
| S100A8 | S100 calcium binding protein A8 |
| SFRP1 | secreted frizzled-related protein 1 |
| SYNM | synemin, intermediate filament protein |
| TMEM97 | transmembrane protein 97 |
| TPBG | trophoblast glycoprotein |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| ZWINT | ZW10 interacting kinetochore protein |
