BRD-K03557653_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K03557653_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAA2 acetyl-CoA acyltransferase 2
ANKRD36B ankyrin repeat domain 36B
BAG3 BCL2-associated athanogene 3
BMP7 bone morphogenetic protein 7
CCDC86 coiled-coil domain containing 86
CELF2 CUGBP, Elav-like family member 2
CEP68 centrosomal protein 68kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CSRP1 cysteine and glycine-rich protein 1
DENND1B DENN/MADD domain containing 1B
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
HIST1H2BG histone cluster 1, H2bg
HMOX1 heme oxygenase 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
ICAM2 intercellular adhesion molecule 2
IER5 immediate early response 5
MAOA monoamine oxidase A
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
RGCC regulator of cell cycle
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A1 solute carrier family 38, member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SQSTM1 sequestosome 1
STC1 stanniocalcin 1
STS steroid sulfatase (microsomal), isozyme S
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM97 transmembrane protein 97
TXNRD1 thioredoxin reductase 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ASPH aspartate beta-hydroxylase
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNF cyclin F
CD24 CD24 molecule
CD9 CD9 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CNN3 calponin 3, acidic
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DSP desmoplakin
GBP1 guanylate binding protein 1, interferon-inducible
HEXIM1 hexamethylene bis-acetamide inducible 1
IER2 immediate early response 2
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
ITGA6 integrin, alpha 6
KIF20A kinesin family member 20A
LOX lysyl oxidase
MARCKSL1 MARCKS-like 1
MTCL1 microtubule crosslinking factor 1
NT5DC2 5'-nucleotidase domain containing 2
NTS neurotensin
PEG10 paternally expressed 10
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
S100A10 S100 calcium binding protein A10
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF6 serine/arginine-rich splicing factor 6
TACSTD2 tumor-associated calcium signal transducer 2
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TNC tenascin C