Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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88 genes differentially expressed following the BRD-K03557653_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
BAG3 | BCL2-associated athanogene 3 |
CCDC47 | coiled-coil domain containing 47 |
CD93 | CD93 molecule |
CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
CLDN3 | claudin 3 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
FGG | fibrinogen gamma chain |
G6PD | glucose-6-phosphate dehydrogenase |
GCLM | glutamate-cysteine ligase, modifier subunit |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HMOX1 | heme oxygenase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPE1 | heat shock 10kDa protein 1 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
IFI30 | interferon, gamma-inducible protein 30 |
MCAM | melanoma cell adhesion molecule |
MMP12 | matrix metallopeptidase 12 |
NNMT | nicotinamide N-methyltransferase |
NPTX2 | neuronal pentraxin II |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
PNKP | polynucleotide kinase 3'-phosphatase |
POPDC3 | popeye domain containing 3 |
RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
RUFY3 | RUN and FYVE domain containing 3 |
SQSTM1 | sequestosome 1 |
STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
TXNRD1 | thioredoxin reductase 1 |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
UGDH | UDP-glucose 6-dehydrogenase |
Symbol | Name |
---|---|
ACTG2 | actin, gamma 2, smooth muscle, enteric |
ADD3 | adducin 3 (gamma) |
AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
AQP1 | aquaporin 1 (Colton blood group) |
ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
BCHE | butyrylcholinesterase |
BMP4 | bone morphogenetic protein 4 |
CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CETN2 | centrin, EF-hand protein, 2 |
CTSH | cathepsin H |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
DACH1 | dachshund family transcription factor 1 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
FABP4 | fatty acid binding protein 4, adipocyte |
FAM129A | family with sequence similarity 129, member A |
FST | follistatin |
GATA2 | GATA binding protein 2 |
GREM1 | gremlin 1, DAN family BMP antagonist |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IL17RB | interleukin 17 receptor B |
KRT5 | keratin 5, type II |
MGST3 | microsomal glutathione S-transferase 3 |
MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
NREP | neuronal regeneration related protein |
OLFM4 | olfactomedin 4 |
OLFML3 | olfactomedin-like 3 |
OSR2 | odd-skipped related transciption factor 2 |
PCP4 | Purkinje cell protein 4 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PIH1D1 | PIH1 domain containing 1 |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
PTX3 | pentraxin 3, long |
RBP1 | retinol binding protein 1, cellular |
RGS2 | regulator of G-protein signaling 2 |
RHOBTB3 | Rho-related BTB domain containing 3 |
S100P | S100 calcium binding protein P |
SFRP1 | secreted frizzled-related protein 1 |
SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
SOX4 | SRY (sex determining region Y)-box 4 |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFPI2 | tissue factor pathway inhibitor 2 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TMEM110 | transmembrane protein 110 |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |