BRD-K03568209_7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c]azepin-1-one_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K03568209_7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c]azepin-1-one_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BMP7 bone morphogenetic protein 7
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL9A2 collagen, type IX, alpha 2
CPE carboxypeptidase E
CREB3L1 cAMP responsive element binding protein 3-like 1
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL6 chemokine (C-X-C motif) ligand 6
DPT dermatopontin
E2F2 E2F transcription factor 2
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
GBP1 guanylate binding protein 1, interferon-inducible
GCG glucagon
GCH1 GTP cyclohydrolase 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
IGHM immunoglobulin heavy constant mu
INSM1 insulinoma-associated 1
KLF5 Kruppel-like factor 5 (intestinal)
KRT19 keratin 19, type I
LGALS4 lectin, galactoside-binding, soluble, 4
LYZ lysozyme
MAPK13 mitogen-activated protein kinase 13
MT1M metallothionein 1M
OAT ornithine aminotransferase
PTX3 pentraxin 3, long
REG1A regenerating islet-derived 1 alpha
RND3 Rho family GTPase 3
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNAI2 snail family zinc finger 2
SPINK4 serine peptidase inhibitor, Kazal type 4
TCL1A T-cell leukemia/lymphoma 1A
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ATP9A ATPase, class II, type 9A
AUTS2 autism susceptibility candidate 2
BASP1 brain abundant, membrane attached signal protein 1
C3 complement component 3
CLEC11A C-type lectin domain family 11, member A
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL14 chemokine (C-X-C motif) ligand 14
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK1 death-associated protein kinase 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
GABARAPL1 GABA(A) receptor-associated protein like 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GOLGA8A golgin A8 family, member A
GOLM1 golgi membrane protein 1
GSTM2 glutathione S-transferase mu 2 (muscle)
HN1 hematological and neurological expressed 1
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
KRT14 keratin 14, type I
KRT17 keratin 17, type I
MAP7 microtubule-associated protein 7
NNMT nicotinamide N-methyltransferase
PDE4B phosphodiesterase 4B, cAMP-specific
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PSIP1 PC4 and SFRS1 interacting protein 1
RGS1 regulator of G-protein signaling 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SRGN serglycin
SRI sorcin
STOM stomatin
TPD52L1 tumor protein D52-like 1
ZBTB18 zinc finger and BTB domain containing 18