BRD-K03651937_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K03651937_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
COLEC12 collectin sub-family member 12
CXCL8 chemokine (C-X-C motif) ligand 8
FAM134B family with sequence similarity 134, member B
FKBP1B FK506 binding protein 1B, 12.6 kDa
GSN gelsolin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IGFBP3 insulin-like growth factor binding protein 3
KRT7 keratin 7, type II
NQO1 NAD(P)H dehydrogenase, quinone 1
PGD phosphogluconate dehydrogenase
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SRGN serglycin
SYT11 synaptotagmin XI
TFF3 trefoil factor 3 (intestinal)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TRIM22 tripartite motif containing 22

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AQP3 aquaporin 3 (Gill blood group)
BTG3 BTG family, member 3
CCND1 cyclin D1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ODC1 ornithine decarboxylase 1
PODXL podocalyxin-like
RHOQ ras homolog family member Q
SIK1 salt-inducible kinase 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TMEM158 transmembrane protein 158 (gene/pseudogene)