BRD-K03670461_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K03670461_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADIRF adipogenesis regulatory factor
C14ORF132 chromosome 14 open reading frame 132
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
INSR insulin receptor
LAPTM5 lysosomal protein transmembrane 5
MAP1B microtubule-associated protein 1B
NQO1 NAD(P)H dehydrogenase, quinone 1
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
SCGB2A2 secretoglobin, family 2A, member 2
TM4SF1 transmembrane 4 L six family member 1

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
CLU clusterin
CST3 cystatin C
CXCL12 chemokine (C-X-C motif) ligand 12
FHL1 four and a half LIM domains 1
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP7 insulin-like growth factor binding protein 7
NNMT nicotinamide N-methyltransferase
PTGDS prostaglandin D2 synthase 21kDa (brain)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFRP1 secreted frizzled-related protein 1
SPRY2 sprouty homolog 2 (Drosophila)
TNS3 tensin 3