BRD-K03736784_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K03736784_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AEBP1 AE binding protein 1
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ATF3 activating transcription factor 3
AZIN1 antizyme inhibitor 1
BAG3 BCL2-associated athanogene 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CNN3 calponin 3, acidic
CP ceruloplasmin (ferroxidase)
CSRP2 cysteine and glycine-rich protein 2
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
GLUL glutamate-ammonia ligase
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HP haptoglobin
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KIF14 kinesin family member 14
LEF1 lymphoid enhancer-binding factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MED13 mediator complex subunit 13
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MIR22HG MIR22 host gene
NXF1 nuclear RNA export factor 1
PDE4B phosphodiesterase 4B, cAMP-specific
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RGS10 regulator of G-protein signaling 10
SERINC5 serine incorporator 5
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SULF1 sulfatase 1
THBD thrombomodulin
TMSB15A thymosin beta 15a
TRBC1 T cell receptor beta constant 1
UGDH UDP-glucose 6-dehydrogenase
WSB1 WD repeat and SOCS box containing 1
YPEL5 yippee-like 5 (Drosophila)
ZEB1 zinc finger E-box binding homeobox 1
ZIC1 Zic family member 1
ZNF394 zinc finger protein 394

decreased expression

Symbol Name
CD320 CD320 molecule
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FLNA filamin A, alpha
FPGS folylpolyglutamate synthase
GATA2 GATA binding protein 2
GNAS GNAS complex locus
HES1 hes family bHLH transcription factor 1
HOXA10 homeobox A10
MRPL12 mitochondrial ribosomal protein L12
MRPS2 mitochondrial ribosomal protein S2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PCNA proliferating cell nuclear antigen
PNMA2 paraneoplastic Ma antigen 2
PPARG peroxisome proliferator-activated receptor gamma
PRMT1 protein arginine methyltransferase 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCAND1 SCAN domain containing 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM223 transmembrane protein 223
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF131 zinc finger protein 131
Funding