Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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95 genes differentially expressed following the BRD-K03814443_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ARL4C | ADP-ribosylation factor-like 4C |
BMP2 | bone morphogenetic protein 2 |
CA2 | carbonic anhydrase II |
CCDC86 | coiled-coil domain containing 86 |
CDKN2A | cyclin-dependent kinase inhibitor 2A |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
DPP4 | dipeptidyl-peptidase 4 |
DUSP1 | dual specificity phosphatase 1 |
EGFR | epidermal growth factor receptor |
EIF5A | eukaryotic translation initiation factor 5A |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
EPHA4 | EPH receptor A4 |
EXT1 | exostosin glycosyltransferase 1 |
GEM | GTP binding protein overexpressed in skeletal muscle |
GJA1 | gap junction protein, alpha 1, 43kDa |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
IDO1 | indoleamine 2,3-dioxygenase 1 |
JUNB | jun B proto-oncogene |
KLF4 | Kruppel-like factor 4 (gut) |
KLK5 | kallikrein-related peptidase 5 |
KLK8 | kallikrein-related peptidase 8 |
LMO4 | LIM domain only 4 |
MAP7 | microtubule-associated protein 7 |
MME | membrane metallo-endopeptidase |
NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PLK2 | polo-like kinase 2 |
PRDX2 | peroxiredoxin 2 |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
RGS1 | regulator of G-protein signaling 1 |
RGS2 | regulator of G-protein signaling 2 |
RND3 | Rho family GTPase 3 |
RNF167 | ring finger protein 167 |
RTN2 | reticulon 2 |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SGK1 | serum/glucocorticoid regulated kinase 1 |
SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
SLPI | secretory leukocyte peptidase inhibitor |
SOCS2 | suppressor of cytokine signaling 2 |
SST | somatostatin |
TAGLN2 | transgelin 2 |
TMSB15A | thymosin beta 15a |
TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TPSAB1 | tryptase alpha/beta 1 |
TPSB2 | tryptase beta 2 (gene/pseudogene) |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
WFDC2 | WAP four-disulfide core domain 2 |
Symbol | Name |
---|---|
AGR2 | anterior gradient 2 |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
ANK2 | ankyrin 2, neuronal |
CD93 | CD93 molecule |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CES1 | carboxylesterase 1 |
CRISP3 | cysteine-rich secretory protein 3 |
DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 |
F13A1 | coagulation factor XIII, A1 polypeptide |
FABP1 | fatty acid binding protein 1, liver |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
HCAR3 | hydroxycarboxylic acid receptor 3 |
IGFBP1 | insulin-like growth factor binding protein 1 |
IL1R2 | interleukin 1 receptor, type II |
IL6ST | interleukin 6 signal transducer |
IQGAP1 | IQ motif containing GTPase activating protein 1 |
KCTD12 | potassium channel tetramerization domain containing 12 |
LDLR | low density lipoprotein receptor |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
MAPK13 | mitogen-activated protein kinase 13 |
MGP | matrix Gla protein |
MUC5B | mucin 5B, oligomeric mucus/gel-forming |
PGD | phosphogluconate dehydrogenase |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PLAC8 | placenta-specific 8 |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PSPH | phosphoserine phosphatase |
PVALB | parvalbumin |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFF3 | trefoil factor 3 (intestinal) |
TM4SF1 | transmembrane 4 L six family member 1 |
TSPAN8 | tetraspanin 8 |
TSPYL5 | TSPY-like 5 |
UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |