BRD-K04389336_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K04389336_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASPN asporin
BGN biglycan
C3 complement component 3
CALD1 caldesmon 1
CLEC5A C-type lectin domain family 5, member A
COL11A1 collagen, type XI, alpha 1
CP ceruloplasmin (ferroxidase)
CRABP1 cellular retinoic acid binding protein 1
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
LIMCH1 LIM and calponin homology domains 1
LTF lactotransferrin
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
METTL7A methyltransferase like 7A
MTUS1 microtubule associated tumor suppressor 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PTPRO protein tyrosine phosphatase, receptor type, O
RCAN2 regulator of calcineurin 2
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
S100A8 S100 calcium binding protein A8
SHB Src homology 2 domain containing adaptor protein B
SPON1 spondin 1, extracellular matrix protein
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DENND2D DENN/MADD domain containing 2D
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GSTM3 glutathione S-transferase mu 3 (brain)
HSPB8 heat shock 22kDa protein 8
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
PLAC8 placenta-specific 8
RHOBTB3 Rho-related BTB domain containing 3
S100A10 S100 calcium binding protein A10
SPOP speckle-type POZ protein
TFF1 trefoil factor 1
Funding