Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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62 genes differentially expressed following the BRD-K04414442_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
ARMCX6 | armadillo repeat containing, X-linked 6 |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
C10ORF10 | chromosome 10 open reading frame 10 |
CPM | carboxypeptidase M |
CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
GIMAP4 | GTPase, IMAP family member 4 |
HMG20B | high mobility group 20B |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
KDM5D | lysine (K)-specific demethylase 5D |
KRT14 | keratin 14, type I |
LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAP2K3 | mitogen-activated protein kinase kinase 3 |
RBPMS | RNA binding protein with multiple splicing |
SFTPB | surfactant protein B |
SMYD3 | SET and MYND domain containing 3 |
SNX11 | sorting nexin 11 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TPSAB1 | tryptase alpha/beta 1 |
TPSB2 | tryptase beta 2 (gene/pseudogene) |
TSPAN7 | tetraspanin 7 |
VAV3 | vav 3 guanine nucleotide exchange factor |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
Symbol | Name |
---|---|
AOX1 | aldehyde oxidase 1 |
ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BCL6 | B-cell CLL/lymphoma 6 |
CA2 | carbonic anhydrase II |
CCK | cholecystokinin |
CD24 | CD24 molecule |
CDV3 | CDV3 homolog (mouse) |
CLIC4 | chloride intracellular channel 4 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
EIF5A | eukaryotic translation initiation factor 5A |
EREG | epiregulin |
F3 | coagulation factor III (thromboplastin, tissue factor) |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
IFRD2 | interferon-related developmental regulator 2 |
KRT8 | keratin 8, type II |
MAP7 | microtubule-associated protein 7 |
NEBL | nebulette |
P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
PAWR | PRKC, apoptosis, WT1, regulator |
PAX5 | paired box 5 |
PCSK1 | proprotein convertase subtilisin/kexin type 1 |
PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
PTPRO | protein tyrosine phosphatase, receptor type, O |
RGCC | regulator of cell cycle |
RHOBTB3 | Rho-related BTB domain containing 3 |
RNF167 | ring finger protein 167 |
S100P | S100 calcium binding protein P |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SRSF6 | serine/arginine-rich splicing factor 6 |
STX1A | syntaxin 1A (brain) |
TCL1A | T-cell leukemia/lymphoma 1A |
TFPI2 | tissue factor pathway inhibitor 2 |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
THBS1 | thrombospondin 1 |
VCAN | versican |