Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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82 genes differentially expressed following the BRD-K04853698_LDN-193189_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABHD2 | abhydrolase domain containing 2 |
ACBD3 | acyl-CoA binding domain containing 3 |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
APP | amyloid beta (A4) precursor protein |
CAST | calpastatin |
CD36 | CD36 molecule (thrombospondin receptor) |
CD9 | CD9 molecule |
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
COL11A1 | collagen, type XI, alpha 1 |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
CTGF | connective tissue growth factor |
CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DUSP6 | dual specificity phosphatase 6 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
FAM198B | family with sequence similarity 198, member B |
G0S2 | G0/G1 switch 2 |
ICAM1 | intercellular adhesion molecule 1 |
IGFBP4 | insulin-like growth factor binding protein 4 |
JMJD6 | jumonji domain containing 6 |
KDM5D | lysine (K)-specific demethylase 5D |
KRT18 | keratin 18, type I |
LEF1 | lymphoid enhancer-binding factor 1 |
LXN | latexin |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MARCKSL1 | MARCKS-like 1 |
MLPH | melanophilin |
MUC5B | mucin 5B, oligomeric mucus/gel-forming |
PDGFC | platelet derived growth factor C |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PLAT | plasminogen activator, tissue |
RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
RNASET2 | ribonuclease T2 |
SOX4 | SRY (sex determining region Y)-box 4 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TM4SF1 | transmembrane 4 L six family member 1 |
TMPRSS2 | transmembrane protease, serine 2 |
TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
TNS3 | tensin 3 |
TRIB2 | tribbles pseudokinase 2 |
VWF | von Willebrand factor |
WT1 | Wilms tumor 1 |
Symbol | Name |
---|---|
AKR1C2 | aldo-keto reductase family 1, member C2 |
ASPA | aspartoacylase |
BEX1 | brain expressed, X-linked 1 |
BLNK | B-cell linker |
CCND2 | cyclin D2 |
CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
CES1 | carboxylesterase 1 |
CLIC4 | chloride intracellular channel 4 |
COBL | cordon-bleu WH2 repeat protein |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
DAPK1 | death-associated protein kinase 1 |
DIO1 | deiodinase, iodothyronine, type I |
DMD | dystrophin |
EML1 | echinoderm microtubule associated protein like 1 |
FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
FGFR3 | fibroblast growth factor receptor 3 |
FGFR4 | fibroblast growth factor receptor 4 |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GLDC | glycine dehydrogenase (decarboxylating) |
GLUL | glutamate-ammonia ligase |
GRWD1 | glutamate-rich WD repeat containing 1 |
GSTA1 | glutathione S-transferase alpha 1 |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
ITM2A | integral membrane protein 2A |
KIAA0922 | KIAA0922 |
MCM3 | minichromosome maintenance complex component 3 |
PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
RAB31 | RAB31, member RAS oncogene family |
REEP1 | receptor accessory protein 1 |
RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
RRAS2 | related RAS viral (r-ras) oncogene homolog 2 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
SWAP70 | SWAP switching B-cell complex 70kDa subunit |
VAV3 | vav 3 guanine nucleotide exchange factor |
XIST | X inactive specific transcript (non-protein coding) |