BRD-K04853698_LDN-193189_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K04853698_LDN-193189_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM10 ADAM metallopeptidase domain 10
APOD apolipoprotein D
BHLHE41 basic helix-loop-helix family, member e41
CST1 cystatin SN
CTAG2 cancer/testis antigen 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
EMX2 empty spiracles homeobox 2
FOXG1 forkhead box G1
GADD45A growth arrest and DNA-damage-inducible, alpha
GNAS GNAS complex locus
HIST1H2BK histone cluster 1, H2bk
HOXB7 homeobox B7
JUN jun proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAN1A1 mannosidase, alpha, class 1A, member 1
MBTPS1 membrane-bound transcription factor peptidase, site 1
PEG10 paternally expressed 10
PTN pleiotrophin
RCAN1 regulator of calcineurin 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
WFS1 Wolfram syndrome 1 (wolframin)

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ACSL3 acyl-CoA synthetase long-chain family member 3
ADCK3 aarF domain containing kinase 3
AEBP1 AE binding protein 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP1 aquaporin 1 (Colton blood group)
AQP9 aquaporin 9
ASPN asporin
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
C4BPA complement component 4 binding protein, alpha
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFH complement factor H
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL10A1 collagen, type X, alpha 1
CPE carboxypeptidase E
CPM carboxypeptidase M
DDIT4 DNA-damage-inducible transcript 4
FHL1 four and a half LIM domains 1
FSTL1 follistatin-like 1
G0S2 G0/G1 switch 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HMOX1 heme oxygenase 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP7 insulin-like growth factor binding protein 7
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
INHBA inhibin, beta A
JCHAIN joining chain of multimeric IgA and IgM
KRT17 keratin 17, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LUM lumican
MAP7 microtubule-associated protein 7
MXRA5 matrix-remodelling associated 5
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRDX2 peroxiredoxin 2
PYCARD PYD and CARD domain containing
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGS5 regulator of G-protein signaling 5
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP4 secreted frizzled-related protein 4
SPARCL1 SPARC-like 1 (hevin)
SULF1 sulfatase 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
THBS2 thrombospondin 2
ZW10 zw10 kinetochore protein
Funding