BRD-K04887706_AKT-inhibitor-1-2_BT20_3_h_10_um Gene Set
Genes
50 genes differentially expressed following the BRD-K04887706_AKT-inhibitor-1-2_BT20_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
C10ORF10
|
chromosome 10 open reading frame 10
|
|
CDK5R1
|
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
|
DST
|
dystonin
|
|
EGR1
|
early growth response 1
|
|
EGR3
|
early growth response 3
|
|
EPS8
|
epidermal growth factor receptor pathway substrate 8
|
|
GEM
|
GTP binding protein overexpressed in skeletal muscle
|
|
IDS
|
iduronate 2-sulfatase
|
|
IGHM
|
immunoglobulin heavy constant mu
|
|
KLF9
|
Kruppel-like factor 9
|
|
KRT23
|
keratin 23, type I
|
|
NEAT1
|
nuclear paraspeckle assembly transcript 1 (non-protein coding)
|
|
NRN1
|
neuritin 1
|
|
PEG10
|
paternally expressed 10
|
|
PHLDA2
|
pleckstrin homology-like domain, family A, member 2
|
|
PTN
|
pleiotrophin
|
|
SC5D
|
sterol-C5-desaturase
|
|
SEPP1
|
selenoprotein P, plasma, 1
|
|
SERPING1
|
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
|
|
SLC19A2
|
solute carrier family 19 (thiamine transporter), member 2
|
|
SPTSSA
|
serine palmitoyltransferase, small subunit A
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
|
UGCG
|
UDP-glucose ceramide glucosyltransferase
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
|
VTCN1
|
V-set domain containing T cell activation inhibitor 1
|
decreased expression
| Symbol |
Name |
|
AKR1B10
|
aldo-keto reductase family 1, member B10 (aldose reductase)
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
|
ALDH3A1
|
aldehyde dehydrogenase 3 family, member A1
|
|
BABAM1
|
BRISC and BRCA1 A complex member 1
|
|
CEACAM5
|
carcinoembryonic antigen-related cell adhesion molecule 5
|
|
CSTA
|
cystatin A (stefin A)
|
|
GPX2
|
glutathione peroxidase 2
|
|
HBB
|
hemoglobin, beta
|
|
HOXA5
|
homeobox A5
|
|
ID1
|
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
|
|
KLF5
|
Kruppel-like factor 5 (intestinal)
|
|
KRT13
|
keratin 13, type I
|
|
KRT6A
|
keratin 6A, type II
|
|
LYZ
|
lysozyme
|
|
MRPL34
|
mitochondrial ribosomal protein L34
|
|
MUC16
|
mucin 16, cell surface associated
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
|
PLOD2
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
|
|
PTX3
|
pentraxin 3, long
|
|
S100P
|
S100 calcium binding protein P
|
|
SFN
|
stratifin
|
|
SLC39A8
|
solute carrier family 39 (zinc transporter), member 8
|
|
TLE4
|
transducin-like enhancer of split 4
|
