| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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107 genes differentially expressed following the BRD-K04887706_AKT-inhibitor-1-2_MDAMB231_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ANXA1 | annexin A1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ASMTL | acetylserotonin O-methyltransferase-like |
| BCR | breakpoint cluster region |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CD200 | CD200 molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CRAT | carnitine O-acetyltransferase |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRIP2 | cysteine-rich protein 2 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DPP4 | dipeptidyl-peptidase 4 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 |
| FADS2 | fatty acid desaturase 2 |
| FBLN1 | fibulin 1 |
| G0S2 | G0/G1 switch 2 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOOK2 | hook microtubule-tethering protein 2 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| INHBA | inhibin, beta A |
| INSIG1 | insulin induced gene 1 |
| ITM2A | integral membrane protein 2A |
| KRT7 | keratin 7, type II |
| LOC100505650 | uncharacterized LOC100505650 |
| MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
| MLF1 | myeloid leukemia factor 1 |
| MMP12 | matrix metallopeptidase 12 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NMU | neuromedin U |
| NNMT | nicotinamide N-methyltransferase |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PAX8 | paired box 8 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PGD | phosphogluconate dehydrogenase |
| PPL | periplakin |
| PRUNE | prune exopolyphosphatase |
| PSPH | phosphoserine phosphatase |
| SCG2 | secretogranin II |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SIK1 | salt-inducible kinase 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SOX17 | SRY (sex determining region Y)-box 17 |
| SPON1 | spondin 1, extracellular matrix protein |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TSC22D3 | TSC22 domain family, member 3 |
| XPO7 | exportin 7 |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADORA2B | adenosine A2b receptor |
| ADRB2 | adrenoceptor beta 2, surface |
| AK4 | adenylate kinase 4 |
| ALB | albumin |
| ALCAM | activated leukocyte cell adhesion molecule |
| APOD | apolipoprotein D |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BMP4 | bone morphogenetic protein 4 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| COL4A6 | collagen, type IV, alpha 6 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CTGF | connective tissue growth factor |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNMBP | dynamin binding protein |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| FABP1 | fatty acid binding protein 1, liver |
| FOSL1 | FOS-like antigen 1 |
| FRZB | frizzled-related protein |
| FZD7 | frizzled class receptor 7 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HES1 | hes family bHLH transcription factor 1 |
| HMGA2 | high mobility group AT-hook 2 |
| HSPB8 | heat shock 22kDa protein 8 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| JCHAIN | joining chain of multimeric IgA and IgM |
| LTF | lactotransferrin |
| MSMB | microseminoprotein, beta- |
| MTERF3 | mitochondrial transcription termination factor 3 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| PFN2 | profilin 2 |
| PLK1 | polo-like kinase 1 |
| POU2AF1 | POU class 2 associating factor 1 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RPL38 | ribosomal protein L38 |
| SFRP1 | secreted frizzled-related protein 1 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TF | transferrin |
| THBS1 | thrombospondin 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TSPAN5 | tetraspanin 5 |
| TUBB2A | tubulin, beta 2A class IIa |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
