Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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115 genes differentially expressed following the BRD-K05104363_PD-184352_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABLIM1 | actin binding LIM protein 1 |
ADGRG1 | adhesion G protein-coupled receptor G1 |
AHNAK | AHNAK nucleoprotein |
ANXA4 | annexin A4 |
ASS1 | argininosuccinate synthase 1 |
C1ORF115 | chromosome 1 open reading frame 115 |
CD99 | CD99 molecule |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
COL4A1 | collagen, type IV, alpha 1 |
CRYAB | crystallin, alpha B |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DSP | desmoplakin |
EFNA1 | ephrin-A1 |
EGFL6 | EGF-like-domain, multiple 6 |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
FAM134B | family with sequence similarity 134, member B |
FNBP1 | formin binding protein 1 |
FOLR1 | folate receptor 1 (adult) |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
HMOX1 | heme oxygenase 1 |
HOXA5 | homeobox A5 |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IFI27 | interferon, alpha-inducible protein 27 |
IFI6 | interferon, alpha-inducible protein 6 |
IL32 | interleukin 32 |
ISG15 | ISG15 ubiquitin-like modifier |
JAK1 | Janus kinase 1 |
KIAA1598 | |
KLF4 | Kruppel-like factor 4 (gut) |
KRT5 | keratin 5, type II |
LAMA3 | laminin, alpha 3 |
LOX | lysyl oxidase |
LPL | lipoprotein lipase |
MAP7 | microtubule-associated protein 7 |
NDRG1 | N-myc downstream regulated 1 |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
PDZK1IP1 | PDZK1 interacting protein 1 |
PHYH | phytanoyl-CoA 2-hydroxylase |
PRUNE2 | prune homolog 2 (Drosophila) |
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
PXDN | peroxidasin |
RHOC | ras homolog family member C |
S100A10 | S100 calcium binding protein A10 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SIDT2 | SID1 transmembrane family, member 2 |
SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
SLC26A3 | solute carrier family 26 (anion exchanger), member 3 |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
TAGLN2 | transgelin 2 |
TCEAL2 | transcription elongation factor A (SII)-like 2 |
TRIM36 | tripartite motif containing 36 |
TTC39A | tetratricopeptide repeat domain 39A |
TXNIP | thioredoxin interacting protein |
UGDH | UDP-glucose 6-dehydrogenase |
Symbol | Name |
---|---|
ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
ADAM28 | ADAM metallopeptidase domain 28 |
ADRB2 | adrenoceptor beta 2, surface |
ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
AREG | amphiregulin |
C7 | complement component 7 |
CCND1 | cyclin D1 |
CD24 | CD24 molecule |
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
CXCL5 | chemokine (C-X-C motif) ligand 5 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
DEFA4 | defensin, alpha 4, corticostatin |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DUSP4 | dual specificity phosphatase 4 |
DUSP6 | dual specificity phosphatase 6 |
ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
EPHA2 | EPH receptor A2 |
EREG | epiregulin |
ETV1 | ets variant 1 |
ETV5 | ets variant 5 |
GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
GOLT1B | golgi transport 1B |
HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
HOPX | HOP homeobox |
HP | haptoglobin |
IER3 | immediate early response 3 |
IRS1 | insulin receptor substrate 1 |
KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
KLK11 | kallikrein-related peptidase 11 |
KRT13 | keratin 13, type I |
MAPK13 | mitogen-activated protein kinase 13 |
MICB | MHC class I polypeptide-related sequence B |
MUC5B | mucin 5B, oligomeric mucus/gel-forming |
NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
NT5E | 5'-nucleotidase, ecto (CD73) |
PDE4B | phosphodiesterase 4B, cAMP-specific |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PLK2 | polo-like kinase 2 |
RBPMS | RNA binding protein with multiple splicing |
RGS2 | regulator of G-protein signaling 2 |
SFRP1 | secreted frizzled-related protein 1 |
SLC38A1 | solute carrier family 38, member 1 |
SPINK5 | serine peptidase inhibitor, Kazal type 5 |
SPRR3 | small proline-rich protein 3 |
SPRY2 | sprouty homolog 2 (Drosophila) |
TCF4 | transcription factor 4 |
TFPI2 | tissue factor pathway inhibitor 2 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TREM1 | triggering receptor expressed on myeloid cells 1 |
TSPAN5 | tetraspanin 5 |
TYMS | thymidylate synthetase |