BRD-K05104363_PD-184352_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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42 genes differentially expressed following the BRD-K05104363_PD-184352_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AQP3 aquaporin 3 (Gill blood group)
CST7 cystatin F (leukocystatin)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
DCLK1 doublecortin-like kinase 1
GCH1 GTP cyclohydrolase 1
ITM2A integral membrane protein 2A
MAP7 microtubule-associated protein 7
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPR3 natriuretic peptide receptor 3
NRCAM neuronal cell adhesion molecule
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
RPS27L ribosomal protein S27-like
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TFPI2 tissue factor pathway inhibitor 2
THAP11 THAP domain containing 11
TNFAIP3 tumor necrosis factor, alpha-induced protein 3

decreased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
ANXA3 annexin A3
CCND1 cyclin D1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
EPHA3 EPH receptor A3
ESR1 estrogen receptor 1
FOSL1 FOS-like antigen 1
HOXB6 homeobox B6
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGHM immunoglobulin heavy constant mu
KIAA1033 KIAA1033
KIF5C kinesin family member 5C
NLGN4X neuroligin 4, X-linked
PHLDA2 pleckstrin homology-like domain, family A, member 2
SNAP25 synaptosomal-associated protein, 25kDa
SOX9 SRY (sex determining region Y)-box 9
SPP1 secreted phosphoprotein 1
TCL1A T-cell leukemia/lymphoma 1A
TLR4 toll-like receptor 4
TNS3 tensin 3
VSNL1 visinin-like 1