BRD-K05104363_PD-184352_HT29_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

100 genes differentially expressed following the BRD-K05104363_PD-184352_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AKR1C3 aldo-keto reductase family 1, member C3
ALOX5 arachidonate 5-lipoxygenase
ATM ATM serine/threonine kinase
ATP9A ATPase, class II, type 9A
BEX4 brain expressed, X-linked 4
BLNK B-cell linker
CD200 CD200 molecule
CD24 CD24 molecule
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CLCA2 chloride channel accessory 2
CXADR coxsackie virus and adenovirus receptor
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAPK1 death-associated protein kinase 1
DNTT DNA nucleotidylexotransferase
DTX4 deltex 4, E3 ubiquitin ligase
F13A1 coagulation factor XIII, A1 polypeptide
FABP6 fatty acid binding protein 6, ileal
FAM134B family with sequence similarity 134, member B
FAM13A family with sequence similarity 13, member A
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GSDMB gasdermin B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGN3 high mobility group nucleosomal binding domain 3
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IGHM immunoglobulin heavy constant mu
IL7R interleukin 7 receptor
ITM2C integral membrane protein 2C
JCHAIN joining chain of multimeric IgA and IgM
KRT7 keratin 7, type II
MEF2C myocyte enhancer factor 2C
MTSS1 metastasis suppressor 1
MYLK myosin light chain kinase
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PHYH phytanoyl-CoA 2-hydroxylase
POU2AF1 POU class 2 associating factor 1
PTPRK protein tyrosine phosphatase, receptor type, K
RND3 Rho family GTPase 3
RPP38 ribonuclease P/MRP 38kDa subunit
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB2A1 secretoglobin, family 2A, member 1
SCPEP1 serine carboxypeptidase 1
SELENBP1 selenium binding protein 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLPI secretory leukocyte peptidase inhibitor
SNX7 sorting nexin 7
TMSB15A thymosin beta 15a
TOX thymocyte selection-associated high mobility group box
TPD52L1 tumor protein D52-like 1
TRIM2 tripartite motif containing 2
TRIM22 tripartite motif containing 22
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VDAC1 voltage-dependent anion channel 1
VTCN1 V-set domain containing T cell activation inhibitor 1
WDTC1 WD and tetratricopeptide repeats 1
WFDC2 WAP four-disulfide core domain 2
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CD44 CD44 molecule (Indian blood group)
CD59 CD59 molecule, complement regulatory protein
CDKN2A cyclin-dependent kinase inhibitor 2A
COL4A2 collagen, type IV, alpha 2
COL9A3 collagen, type IX, alpha 3
CXCR4 chemokine (C-X-C motif) receptor 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP2 dual specificity phosphatase 2
EAPP E2F-associated phosphoprotein
EIF1AX eukaryotic translation initiation factor 1A, X-linked
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
HOMER1 homer scaffolding protein 1
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
LPL lipoprotein lipase
NAP1L1 nucleosome assembly protein 1-like 1
NOTCH2 notch 2
NPM3 nucleophosmin/nucleoplasmin 3
NUP98 nucleoporin 98kDa
ODC1 ornithine decarboxylase 1
PDHX pyruvate dehydrogenase complex, component X
PHLDA1 pleckstrin homology-like domain, family A, member 1
S100P S100 calcium binding protein P
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SRM spermidine synthase
SSFA2 sperm specific antigen 2
TFF1 trefoil factor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TUBB2A tubulin, beta 2A class IIa
UBE2S ubiquitin-conjugating enzyme E2S
Funding